Monthly Archives: March 2012

RNA-Seq of Bacteria

A Team of researchers at the Broad Institute set out  to establish a robust and scalable RNA-seq process applicable to cultured bacteria as well as to complex community transcriptomes. They  determined that an effective process should: a)      reduce rRNA sequences ...

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RNA-Seq at AACR 2012

The annual meeting of the American Association of Cancer Research (AACR) will be held next week in Chicago.  RNA-Seq is one of many new technologies enabling significant discoveries in the areas of cancer research, diagnosis and treatment.  Here is just ...

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Roche vs Illumina – Round 3

Roche is increasing its offer to purchase Illumina from $44.50 to $51 per share. This represents a deal valued at almost $6.6 billion, cash.  Amazing! Though no deal has yet been struck, because this is a cash deal that has been ...

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Insights into Chinese prostate cancer with RNA-seq

Prostate cancer remains a leading cause of cancer morbidity and mortality in men, accounting for approximately one million new cases and 260 000 deaths per year worldwide. Incidence and mortality rates vary widely across geographic regions and ethnic groups. In ...

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Maize (Zea mays L.) Genome Diversity as Revealed by RNA-Sequencing

Maize is rich in genetic and phenotypic diversity. Understanding the sequence, structural, and expression variation that contributes to phenotypic diversity would facilitate more efficient varietal improvement. RNA based sequencing (RNA-seq) is a powerful approach for transcriptional analysis, assessing sequence variation, ...

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RNA-Seq Tutorial from the iPlant Collaborative

iPlant Collaborative is a community of researchers, educators, and students working to enrich all plant sciences through the development of cyberinfrastructure – the physical computing resources, collaborative environment, virtual machine resources, and interoperable analysis software and data services– that are ...

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RNA-Seq Data Analysis – Poll Results

Initially we asked: Do we yet have a firm handle on the most appropriate/accurate pipeline for analysis of RNA-Seq datasets?  Almost 90% of our readers said NO.  So in our last poll, we tried to dig a little deeper and ...

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Sugar Beet Transcriptome

Sugar beet (Beta vulgaris sp. vulgaris) crops account for about 30% of world sugar. Sugar yield is compromised by reproductive growth hence crops must remain vegetative until harvest. There is no sugar beet reference genome, or public expression array platforms. ...

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