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DynaMIT – the dynamic motif integration toolkit

DynaMIT – the dynamic motif integration toolkit

De-novo motif search is a frequently applied bioinformatics procedure to identify and prioritize recurrent elements in sequences sets for biological investigation, such as the ones derived from high-throughput differential expression experiments. Several algorithms have been developed to perform motif search, ...

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RNAcop – optimizing RNA structures by sequence extensions

RNAcop – optimizing RNA structures by sequence extensions

A key aspect of RNA secondary structure prediction is the identification of novel functional elements. This is a challenging task because these elements typically are embedded in longer transcripts where the borders between the element and flanking regions have to ...

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Proteomics Informed by Transcriptomics

Proteomics Informed by Transcriptomics

With the recent advent of RNA-seq technology the proteomics community has begun to generate sample-specific protein databases for peptide and protein identification, an approach we call proteomics informed by transcriptomics (PIT). This approach has gained a lot of interest, particularly ...

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