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The Ensembl gene annotation system

The Ensembl gene annotation system

The Ensembl gene annotation system has been used to annotate over 70 different vertebrate species across a wide range of genome projects. Furthermore, it generates the automatic alignment-based annotation for the human and mouse GENCODE gene sets. The system is ...

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Pseudotime Estimation – Deconfounding Single Cell Time Series

Pseudotime Estimation – Deconfounding Single Cell Time Series

Repeated cross-sectional time series single cell data confound several sources of variation, with contributions from measurement noise, stochastic cell-to-cell variation and cell progression at different rates. Time series from single cell assays are particularly susceptible to confounding as the measurements ...

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CONDOP – an R package for CONdition-Dependent Operon Predictions

CONDOP – an R package for CONdition-Dependent Operon Predictions

The use of high-throughput RNA sequencing to predict dynamic operon structures in prokaryotic genomes has recently gained popularity in bioinformatics. Researchers from the Finnish Institute of Occupational Health provide the R implementation of a novel method that uses transcriptomic features ...

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