Pathway Analysis

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Inferring metabolic pathway activity levels from RNA-Seq data

Inferring metabolic pathway activity levels from RNA-Seq data

Assessing pathway activity levels is a plausible way to quantify metabolic differences between various conditions. This is usually inferred from microarray expression data. Wide availability of NGS technology has triggered a demand for bioinformatics tools capable of analyzing pathway activity ...

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gsa4mirna – Integrated gene set analysis for microRNA studies

gsa4mirna – Integrated gene set analysis for microRNA studies

Functional interpretation of miRNA expression data is currently done in a three step procedure: select differentially expressed miRNAs, find their target genes, and carry out gene set overrepresentation analysis Nevertheless, major limitations of this approach have already been described at ...

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