Splicing and Junction Mapping

Feed Subscription

RVboost: RNA-Seq variants prioritization using a boosting method

RVboost: RNA-Seq variants prioritization using a boosting method

RNA-Seq has become the method of choice to quantify genes and exons, discover novel transcripts, and detect fusion genes. However, reliable variant identification from RNA-Seq data remains challenging due to the complexities of the transcriptome, the challenges of accurately mapping ...

Read More »

JAGuaR: Junction Alignments to Genome for RNA-Seq Reads

JAGuaR: Junction Alignments to Genome for RNA-Seq Reads

JAGuaR is an alignment protocol for RNA-seq reads that uses an extended reference to increase alignment sensitivity. It uses BWA to align reads to the genome and reference transcript models (including annotated exon-exon junctions) specifically allowing for the possibility of ...

Read More »

ARH-seq – identification of differential splicing in RNA-seq data

ARH-seq – identification of differential splicing in RNA-seq data

The computational prediction of alternative splicing from high-throughput sequencing data is inherently difficult and necessitates robust statistical measures because the differential splicing signal is overlaid by influencing factors such as gene expression differences and simultaneous expression of multiple isoforms amongst ...

Read More »
Scroll To Top