Splicing and Junction Mapping

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Transcriptome Sequencing for the Detection of Chimeric Transcripts

Transcriptome Sequencing for the Detection of Chimeric Transcripts

The occurrence of chimeric transcripts has been reported in many cancer cells and seen as potential biomarkers and therapeutic targets. Modern high-throughput sequencing technologies offer a way to investigate individual chimeric transcripts and the systematic information of associated gene expressions ...

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FuMa – reporting overlap in RNA-seq detected fusion genes

FuMa – reporting overlap in RNA-seq detected fusion genes

A new generation of tools that identify fusion genes in RNA-seq data is limited in either sensitivity and or specificity. To allow further downstream analysis and to estimate performance, predicted fusion genes from different tools have to be compared. However, ...

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