Splicing and Junction Mapping

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Improved Transcript Isoform Discovery using ORF Graphs

Improved Transcript Isoform Discovery using ORF Graphs

High-throughput sequencing of RNA in vivo facilitates many applications, not the least of which is the cataloging of variant splice isoforms of protein-coding messenger RNAs. While many solutions have been proposed for reconstructing putative isoforms from deep sequencing data, these ...

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