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Evolutionary Character of Alternative Splicing in Plants

Evolutionary Character of Alternative Splicing in Plants

Alternative splicing (AS) is one of the most important ways to enhance the functional diversity of genes. Huge amounts of data have been produced by microarray, expressed sequence tag, and RNA-seq, and plenty of methods have been developed specifically for ...

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Comparative analysis of single-cell RNA-sequencing methods

Comparative analysis of single-cell RNA-sequencing methods

Single-cell mRNA sequencing (scRNA-seq) allows to profile heterogeneous cell populations, offering exciting possibilities to tackle a variety of biological and medical questions. A range of methods has been recently developed, making it necessary to systematically compare their sensitivity, accuracy, precision ...

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Targeted LncRNA Sequencing

Targeted LncRNA Sequencing

Sequencing-based whole-transcriptome analysis (i.e., RNA-Seq) can be a powerful tool when used to measure gene expression, detect novel transcripts, characterize transcript isoforms, and identify sequence polymorphisms. However, this method can be inefficient when the goal is to study only one ...

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