Publications

Feed Subscription

RNA-Seq dispels link between viral infection and brain tumors

RNA-Seq dispels link between viral infection and brain tumors

Next generation sequencing (NGS) can globally interrogate the genetic composition of biological samples in an unbiased yet sensitive manner. Researchers from Tulane University utilized the capabilities of NGS to investigate the reported association between glioblastoma multiforme (GBM) and human cytomegalovirus ...

Read More »

RNA-Seq reveals shortcomings of experimentation models

RNA-Seq reveals shortcomings of experimentation models

Microglia are resident myeloid cells in the CNS that are activated by infection, neuronal injury, and inflammation. Established BV2 microglial cell lines have been the primary in vitro models used to study neuroinflammation for more than a decade because they ...

Read More »

Single cell transcriptomics of the human endocrine pancreas

Single cell transcriptomics of the human endocrine pancreas

Human pancreatic islets consist of multiple endocrine cell types. To facilitate the detection of rare cellular states and uncover population heterogeneity, UPENN School of Medicine researchers performed single-cell RNA-sequencing on islets from multiple deceased organ donors, including children, healthy adults, ...

Read More »

An evaluation of microRNA alignment techniques

An evaluation of microRNA alignment techniques

Genomic alignment of small RNA (smRNA) sequences such as microRNAs poses considerable challenges due to their short length (∼21 nucleotides [nt]) as well as the large size and complexity of plant and animal genomes. While several tools have been developed ...

Read More »
Scroll To Top