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Understanding the differences between microarray and RNA-Seq technologies for measuring gene expression is necessary for informed design of experiments and choice of data analysis methods

Understanding the differences between microarray and RNA-Seq technologies for measuring gene expression is necessary for informed design of experiments and choice of data analysis methods

Previous comparisons between microarrays and RNA-Seq have come to sometimes contradictory conclusions, which researchers from Princeton University suggest result from a lack of attention to the intensity-dependent nature of variation generated by the technologies. To examine this trend, they carried ...

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GTEx publishes results from RNA-Seq pilot study

GTEx publishes results from RNA-Seq pilot study

Human genomes show extensive genetic variation across individuals, but we have only just started documenting the effects of this variation on the regulation of gene expression. Furthermore, only a few tissues have been examined per genetic variant. In order to ...

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