Review Publications

Strategies to Identify Natural Antisense Transcripts

rna-seq

Natural antisense transcripts, originally considered as transcriptional noises arising from so-called “junk DNA”, are recently recognized as important modulators for gene regulation. They are prevalent in nearly all realms of life and have been found to modulate gene expression positively ...

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How to standardize the small RNA-Seq workflow for reliable biomarker signatures in the age of liquid biopsies

Small RNA-Seq has emerged as a powerful tool in transcriptomics, gene expression profiling and biomarker discovery. Sequencing cell-free nucleic acids, particularly microRNA (miRNA), from liquid biopsies additionally provides exciting possibilities for molecular diagnostics, and might help establish disease-specific biomarker signatures. ...

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