Tiling arrays have been the tool of choice for probing an organism’s transcriptome without prior assumptions about the transcribed regions, but RNA-Seq is becoming a viable alternative as the costs of sequencing continue to decrease. Understanding the relative merits of these technologies will help researchers select the appropriate technology for their needs. (read more… )
Agarwal A et al. (2010) Comparison and calibration of transcriptome data from RNA-Seq and tiling arrays. BMC Genomics [Epub ahead of print].