Events

 

QuickMIRSeq: a pipeline for quick and accurate quantification of both known miRNAs and isomiRs

http://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-017-1601-4 Genome-wide miRNA expression data can be used to study miRNA dysregulation comprehensively. Although many open-source tools for microRNA (miRNA)-seq data analyses are available, challenges remain in accurate miRNA quantification from large-scale miRNA-seq dataset. We implemented a pipeline called QuickMIRSeq ...

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RNA-Seq reveals the multilineage communication that regulates human liver bud development from pluripotency

rna-seq

Conventional two-dimensional differentiation from pluripotency fails to recapitulate cell interactions occurring during organogenesis. Three-dimensional organoids generate complex organ-like tissues; however, it is unclear how heterotypic interactions affect lineage identity. Here researchers from the Max Planck Institute for Evolutionary Anthropology use ...

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