Expression Analysis Announces RNA-SEQ Grant Program

Expression Analysis

DURHAM, N.C.–(BUSINESS WIRE)–EA announced it is working with Golden Helix and Illumina to offer three (3) fully-funded grants for RNA-Seq studies and data analysis to support cutting-edge projects that show promise in identifying genetic elements important to enhance the understanding of disease and improve human health. For the studies selected, Expression Analysis will perform the sequencing and provide primary and secondary data analysis; Golden Helix will provide cloud-based secondary analysis tools and storage, plus end-user tertiary analysis tools; and, Illumina will provide the products required for the study. In all cases, there is no cost to the grant recipients.

“We’re excited to work with EA and Illumina on these grants to help three research groups capitalize on the power of RNA-seq technology without this daunting concern.”

RNA-Seq is a cDNA sequencing application that generates a more comprehensive, quantitative and less biased view of the transcriptome when compared to microarray-based technologies.

“RNA sequencing has clear advantages over existing approaches – delivering detection of novel biology not possible using microarrays. The goal of these grants is to introduce researchers to the many benefits of RNA-Seq and to incorporate this method into their research so they can experience its biological advantages first hand,” stated Steve McPhail, CEO of EA.

The informatics challenges associated with NGS-based research are well known, posing a significant barrier to the broad adoption of RNA-seq. Overcoming these challenges has been a particularly difficult step on the path to realizing the full value of this promising technology.

“Many researchers turn away from RNA-Seq studies simply because the informatics are unmanageable,” said Andy Ferrin, EVP of Business Development and Services at Golden Helix. “We’re excited to work with EA and Illumina on these grants to help three research groups capitalize on the power of RNA-seq technology without this daunting concern.”

Projects should demonstrate strong evidence that the study design and analysis proposed are likely to have the power to detect genetic factors affecting the trait under study. There will be one (1) grant awarded in each of the following categories:

– Biomarker discovery using whole transcriptome sequencing

– Developmental coding and non-coding RNA expression

– RNA-Seq analysis of FFPE samples

Applications for the grant are due by April 13, 2012 and the awardees will be notified no later than May 15, 2012. For more information about the program, including application requirements and materials, visit

About Expression Analysis

EA ( provides whole genome to focused set gene expression and genotyping assays along with DNA sequencings services and bioinformatics support. Platforms utilized include Affymetrix, Agilent, Fluidigm, Illumina, Ion Torrent, Raindance Technologies and Pacific Biosciences. Expression Analysis offers solutions for challenging specimens such as whole blood and FFPE tissues, as well as nucleic acid isolation and data analysis services. Our quality system follows CLSI guidelines and our CLIA-registered laboratory supports GLP compliance. EA is committed to the development and use of genomic data to improve the human condition with emphasis on enhancing the diagnosis, treatment and management of complex disease.


Expression Analysis
Karen Michailo, 919-287-4277
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