CLARiENT, a GE Healthcare company
At Clarient, we combine innovative diagnostic technologies with world-class pathology expertise to assess and characterize cancer. Our mission is to become the leader in cancer diagnostics by dedicating ourselves to collaborative relationships with the healthcare community to translate cancer discovery and research into better patient care. Our principal customers include pathologists, oncologists, hospitals and biopharmaceutical companies.
The rise of individualized medicine as the new direction in oncology has created the need for a centralized resource providing leading diagnostic technologies, such as flow cytometry and molecular testing. Clarient is that resource, with a state-of-the-art commercial cancer laboratory providing the most advanced oncology testing and diagnostic services. We are also developing new, proprietary companion” diagnostic markers for therapeutics in breast, prostate, lung and colon cancers, and leukemia/lymphoma.
We are taking cancer personally.
What do you envision for your future At GE Healthcare, we strive to see life more clearly. Our “healthymagination” vision for the future invites the world to join us on our journey as we continuously develop innovations focused on reducing healthcare costs, increasing access and improving quality and efficiency around the world.
We are a $17 billion unit of General Electric Company (NYSE: GE), employing more than 46,000 people worldwide and serving healthcare professionals in more than 100 countries. We believe in our strategy – and we”d like you to be a part of it. As a global leader, GE can bring together the best in science, technology, business and people to help solve one of the world”s toughest challenges and shape a new age of healthcare.
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Posted Position Title Bioinformatician
Career Level Experienced
Function Segment Clinical Development
Location(s) Where Opening Is Available United States
U.S. State, China or Canada Provinces California
City Aliso Viejo
Postal Code 92656-1460
Relocation Expenses No
Role Summary/Purpose GE is an equal opportunity employer, offering a great work environment, challenging career opportunities, professional training and competitive compensation.
Join our team of bioinformatics scientists responsible for developing computational methods and infrastructure to support biomarker discovery. This role will be responsible for analysis of next-generation sequence datasets to identify variants and associated biological pathways. In addition, this role will also be responsible for developing automated sequence analysis pipelines for genome assembly and processing of WES and RNA-Seq datasets.
Essential Responsibilities An overall responsibility for this role is to go well-beyond primary sequence analysis to discover biomarker signatures indicative of underlying disease mechanisms.
.Implement automated pipelines for processing NGS datasets which include WGS, WES and RNA-Seq
.Perform variant analysis and provide pathway-level summary and clinical significance
.Develop or extend algorithms for extracting driver mutations to discover novel or alternate pathways
.Work with external collaborators to provide data analysis support
.Encapsulate automated analysis pipelines into well-defined software services
.Implement software and hardware infrastructure for NGS data processing
* Ph.D. (Doctor of Philosophy) in a biological life science
* At least 4 years of experience in hands-on NGS data analysis in academic or industrial setting
* Demonstrated abilities in delivering on goal-driven and time-bound projects
* Track record of working in collaborative teams
* Must be prolific in computer programming languages such as Java or C++ and scripting languages like Python or Perl.
* Must have experience with relational database systems
Additional Eligibility Qualifications GE will only employ those who are legally authorized to work in the United States for this opening. Any offer of employment is conditioned upon the successful completion of a background investigation and drug screen.
* Experience in hands-on biomarker discovery and pathway analysis, preferably in oncology
* Experience in discovery and analysis of miRNA
* Quality peer-reviewed publications and/or patents