Previous studies have demonstrated the utility of microarray expression analysis to identify potential microRNA targets. Nevertheless, technical limitations intrinsic to this platform constrain its ability to fully exploit the potential ...
Read More »RNA-SEQ NEWS
Ensembl Update (e58) with RNA-Seq Data
Zebrafish RNASeq models (Zebrafish) A new set of gene models made using RNA-Seq data from 9 tissues. The gene set has exon and transcript level RPKM values for each tissue ...
Read More »DESeq – Digital gene expresion analysis based on the negative binomial distribution
Motivation: High throughput nucleotide sequencing provides quantitative readouts in assays for RNA expression (RNA-Seq), protein-DNA binding (ChIP-Seq), cell counting. Statistical inference of differential signal in these data needs to take ...
Read More »MapPER – A New Tool for Aligning Paired-end RNA-seq Data
A Probabilistic Framework for Aligning Paired-end RNA-seq Data Motivation: The RNA-seq paired-end read (PER) protocol samples transcript fragments longer than the sequencing capability of today’s technology by sequencing just the ...
Read More »Featured Review Articles – Transcriptomics
Transcriptomics: Throwing light on dark matter Louisa Flintoft Nature Reviews Genetics 11, 455-455 (July 2010) Transcriptomics: Common disease pathogenesis pathways Gemma K. Alderton Nature Reviews Genetics 11, 386-386 (June 2010) ...
Read More »Featured RNA-SEQ Events
Jobs
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Featured RNA-Seq Job – Bioinformatics/Scientist RNA Biology (NCI)
We are looking for a Bioinformatics/Scientist to provide dedicated bioinformatic support to the newly formed RNA Biology Laboratory in the Center for Cancer Research, National Cancer Institute. The RNA Biology Laboratory carries out cutting-edge...
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Featured RNA-Seq Job – Bioinformatics Scientist
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Postdoctoral fellowship in genetic epidemiology
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Featured RNA-Seq Job – Research Associate
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Open position for a biostatistician / computational biologist
Industry News
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Veracyte to collaborate with Loxo Oncology on RNA sequencing-based Afirma Xpression Atlas
Veracyte, Inc. today announced a research collaboration through which Loxo Oncology will access Veracyte’s new Afirma® Xpression Atlas platform to advance its development of highly selective medicines for patients with genetically defined...
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H3 Biomedicine publishes comprehensive analysis of RNA splicing factor genes in multiple types of cancer
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New data suggests Veracyte’s RNA-Seq based Afirma GSC can help patients avoid unnecessary thyroid surgery
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Newest software release improves the sensitivity of the Iso-Seq method to characterize an organism’s transcriptome
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Cofactor Genomics launches Paragon, an RNA sequencing-based solid tumor immune profiling assay