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May
26
Gene Expression Study Points to Common Transcription Shifts in Autistic Brains
From GenomeWeb
In a paper published online in Nature this week, a team led by investigators at the University of California, Los Angeles, reports its use of gene co-expression network analysis to identify “differences in transcriptome organization between autistic and normal brain.” Furthermore, using RNA-seq and a published genome-wide association study for autism, the team found evidence to support the involvement of the neuronal specific splicing factor A2BP1 and other known susceptibility genes in autism.
(read more… )
Voineagu I, Wang X, Johnston P, Lowe JK, Tian Y, Horvath S, Mill J, Cantor RM, Blencowe BJ, Geschwind DH. (2011) Transcriptomic analysis of autistic brain reveals convergent molecular pathology. Nature [Epub ahead of print]. [abstract]
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Hi,
I’m in the middle of writing a post about this study, and I wondered if you could tell from the article what the resolution is on the microarray they used.
(I’ve been to Illumina’s website but cannot tell which of their products these researchers used).