Seeking a highly motivated individual with expertise in gene expression analysis (RNA-Seq)

Sr. Research Associate
8109BR
Computational Genomics
Boston, MA
We are seeking a highly motivated individual with expertise in gene expression analysis (RNA-Seq), cancer genomics (including cancer cell line screens or somatic mutation analysis), statistical genetics (germline association studies), evolutionary sequence analysis, or text mining to join Vertex’s research site in Boston, MA. You will report directly to the Sr. Director of Vertex’s newly created Computational Genomics department. Depending on qualifications and level of expertise you will be primarily focused on developing and applying computational and statistical methods to analyze large data sets in order to help identify potential lead compounds and molecular targets.  Responsibilities include but are not limited to the following:  Enable, perform and support computational analyses for a wide range of research projects.  Evaluate commercial software, and recommend purchases.  Work with the internal methods development group to develop and deploy relevant software tools.
MS degree in human/statistical genetics, (cancer) genomics, or a related field in the biological data sciences.  0-4 years of productive, relevant post-doctoral and/or industry experience.  Solid understanding of statistics and expertise in R, Bioconductor, relational databases (SQL), and one or more scripting languages: (Python, Perl, BioPython, BioPerl).  In-depth knowledge of genome annotation (e.g. Ensembl and UCSC) and pathway biology resources.  A proven track record in computational analysis of large “omics” data sets (e.g. RNA-seq, whole-genome/exome sequencing).  Excellent communication skills and ability to work both independently and collaboratively across our global research organization.

Vertex is a global biotechnology company that aims to discover, develop and commercialize innovative medicines so people with serious diseases can lead better lives. In addition to our clinical development programs focused on cystic fibrosis, Vertex has more than a dozen ongoing research programs aimed at other serious and life-threatening diseases.

Founded in 1989 in Cambridge, Mass., Vertex today has research and development sites and commercial offices in the United States, Europe, Canada and Australia. For four years in a row, Science magazine has named Vertex one of its Top Employers in the life sciences. For additional information and the latest updates from the Company, please visit www.vrtx.com.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

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