Single-cell RNA-Seq Gaining Steam

rna-seq In general, agreement among scRNA-Seq data analysis tools in calling DE genes is not high (2/15/2019)- The analysis of single-cell RNA sequencing (scRNAseq) data plays an important role in understanding the intrinsic and extrinsic cellular processes in biological and biomedical research. One significant effort in this area is the detection of...
rna-seq Improved RNA data visualization method gets to the bigger picture faster (2/14/2019)- Like going from a pinhole camera to a Polaroid, a significant mathematical update to the formula for a popular bioinformatics data visualization method will...
rna-seq New microfluidics platform separates cell types for RNA sequencing (2/6/2019)- A team led by scientists at the Broad Institute, MIT, and Massachusetts General Hospital has developed a prototype device that uses microfluidics to sort cell types extracted from clinical samples for RNA sequencing. This platform allows us to isolate specific cell...
1CellBio and Partek Deliver Easy-to-use Single Cell Analysis Solution (1/28/2019)- 1CellBio and Partek Deliver Easy-to-use Single Cell Analysis Solution Powerful Single Cell Bioinformatics Solution in a Graphical User Interface LOUIS and CAMBRIDGE — 1/24/2019 — 1CellBio Inc. and Partek Incorporated have partnered to deliver a data analysis pipeline for the inDrop™ System for use within Partek® Flow® bioinformatics software. The pipeline allows users to pre-process ...
rna-seq Sircel – barcode identification for single cell genomics (1/23/2019)- Single-cell sequencing experiments use short DNA barcode ‘tags’ to identify reads that originate from the same cell. In order to recover single-cell information from such experiments, reads must be...
rna-seq Elegant trick improves single-cell RNA sequencing (1/2/2019)- Droplet microfluidics has revolutionized single-cell RNA sequencing, offering a low-cost, high-throughput method for single-cell genomics. However, this method has been limited in its ability to capture complete RNA transcription information. Researchers at Cornell – led by Iwijn De Vlaminck...
rna-seq Featured RNA-Seq Job – Single Cell Bioinformatician (12/27/2018)- Emeryville, CA R&D Life Sciences Full-time Berkeley Lights: The power of engineering, brought to life. Berkeley Lights, Inc. is enabling precise cell by cell selection and manipulation to empower: cell line development, antibody discovery and engineering, and manufacturing of personalized cellular therapies. Founded in 2011, Berkeley Lights, Inc. delivers breakthrough platforms and devices that fundamentally ...
rna-seq The unique genetic makeup of myeloma tumor cells revealed by single cell RNA-Seq (12/7/2018)- Cancer arises when cells lose control. Deciphering the "blueprint" of cancer cells - outlining how cancer cells hijack specific pathways for uncontrolled proliferation - will lead to more efficient ways to fight it. Joint effort of scientists from the Weizmann Institute of Science and clinicians from major hemato-oncology departments in Israel succeeded...
rna-seq Advantages of single-nucleus over single-cell RNA sequencing of adult kidney (12/6/2018)- A challenge for single-cell genomic studies in kidney and other solid tissues is generating a high-quality single-cell suspension that contains rare or difficult-to-dissociate cell types and is free of both RNA degradation and artifactual transcriptional stress...
RNA Sequencing gives new insights into formation of neurons in mammalian adult brain (12/6/2018)- A team of researchers at Baylor College of Medicine, the Texas Heart Institute and Texas Children’s Hospital has developed a powerful new approach to understand the formation of new neurons in the mammalian adult brain. Published in the journal...

A slew of recent high profile papers and upcoming conferences highlight the growing interest in single-cell transcriptomics.