Tag Archives: alternative splicing

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The dark matter of the cancer genome has been largely neglected

The dark matter of the cancer genome has been largely neglected

Cancer is a disease of the genome caused by oncogene activation and tumor suppressor gene inhibition. Deep sequencing studies including large consortia such as TCGA and ICGC identified numerous tumor-specific mutations not only in protein-coding sequences but also in non-coding ...

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Evolutionary Character of Alternative Splicing in Plants

Evolutionary Character of Alternative Splicing in Plants

Alternative splicing (AS) is one of the most important ways to enhance the functional diversity of genes. Huge amounts of data have been produced by microarray, expressed sequence tag, and RNA-seq, and plenty of methods have been developed specifically for ...

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