Tag Archives: breast cancer

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Isoform-level gene expression patterns in single-cell RNA-sequencing data

Isoform-level gene expression patterns in single-cell RNA-sequencing data

RNA-sequencing of single-cells enables characterization of transcriptional heterogeneity in seemingly homogenous cell populations. In this study, reseachers from the Karolinska Institute propose and apply a novel method, ISOform-Patterns (ISOP), based on mixture modeling, to characterize the expression patterns of pairs ...

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RNA-Seq Identifies Gene Transcription Signatures that Predict Survival after Tamoxifen, CAF Chemotherapy

RNA-Seq Identifies Gene Transcription Signatures that Predict Survival after Tamoxifen, CAF Chemotherapy

from CanceTherapyAdvisor by Bryant Furlow SAN ANTONIO—Next generation whole-genome expression analysis with RNA sequencing (NGS) identified gene-expression biomarkers associated with survival among postmenopausal women with estrogen receptor-positive (ER+), node-positive breast cancer treated with tamoxifen or tamoxifen plus cyclophosphamide, dozorubicin (Adriamycin), ...

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