Tag Archives: deep sequencing

Feed Subscription

Computer-assisted annotation of small RNA transcriptomes

Computer-assisted annotation of small RNA transcriptomes

Small noncoding RNAs (sncRNAs) are widely expressed in the cell of almost all known species. Most sncRNAs appear to have regulatory roles, ranging from facilitating RNA production and modifications (e.g., snoRNAs) to control of mRNA stability and translational efficiency (e.g., ...

Read More »

Biases in small RNA deep sequencing data

Biases in small RNA deep sequencing data

High-throughput RNA sequencing (RNA-seq) is considered a powerful tool for novel gene discovery and fine-tuned transcriptional profiling. The digital nature of RNA-seq is also believed to simplify meta-analysis and to reduce background noise associated with hybridization-based approaches. The development of ...

Read More »
Scroll To Top