Tag Archives: differential expression

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www.rnaseq.wiki

www.rnaseq.wiki

Massively parallel RNA sequencing (RNA-seq) has rapidly become the assay of choice for interrogating RNA transcript abundance and diversity. This article provides a detailed introduction to fundamental RNA-seq molecular biology and informatics concepts. The authors make available open-access RNA-seq tutorials ...

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LFC – a count ratio model to estimate fold changes

LFC – a count ratio model to estimate fold changes

Various biases affect high-throughput sequencing read counts. Contrary to the general assumption, researchers from Ludwig-Maximilians-University Munich show that bias does not always cancel out when fold changes are computed and that bias affects more than 20% of genes that are ...

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