Tag Archives: differential expression

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The landscape of long noncoding RNAs in the human transcriptome

The landscape of long noncoding RNAs in the human transcriptome

Long noncoding RNAs (lncRNAs) are emerging as important regulators of tissue physiology and disease processes including cancer. To delineate genome-wide lncRNA expression, researchers at the University of Michigan curated 7,256 RNA sequencing (RNA-seq) libraries from tumors, normal tissues and cell ...

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Quantitative analysis of bacterial transcriptomes with RNA-seq

Quantitative analysis of bacterial transcriptomes with RNA-seq

RNA sequencing has emerged as the premier approach to study bacterial transcriptomes. While the earliest published studies analyzed the data qualitatively, the data are readily digitized and lend themselves to quantitative analysis. High-resolution RNA sequence (RNA-seq) data allows transcriptional features ...

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PANDORA – Systematic integration of RNA-Seq statistical algorithms

PANDORA – Systematic integration of RNA-Seq statistical algorithms

RNA-Seq is gradually becoming the standard tool for transcriptomic expression studies in biological research. Although considerable progress has been recorded in the development of statistical algorithms for the detection of differentially expressed genes using RNA-Seq data, the list of detected ...

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