Tag Archives: differential expression

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Quantitative analysis of bacterial transcriptomes with RNA-seq

Quantitative analysis of bacterial transcriptomes with RNA-seq

RNA sequencing has emerged as the premier approach to study bacterial transcriptomes. While the earliest published studies analyzed the data qualitatively, the data are readily digitized and lend themselves to quantitative analysis. High-resolution RNA sequence (RNA-seq) data allows transcriptional features ...

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miRNA Temporal Analyzer (mirnaTA) – for identifying differentially expressed microRNAs in temporal studies using normal quantile transformation

miRNA Temporal Analyzer (mirnaTA) – for identifying differentially expressed microRNAs in temporal studies using normal quantile transformation

Many open-source bioinformatics tools to identify existing and/or discover novel miRNAs in next-generation sequencing (NGS) reads have become available. While miRNA identification and discovery tools are significantly improved, the development of miRNA differential expression analysis tools, especially in temporal studies, ...

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Empowered by Maverix, Biologist Uses RNA-seq to Understand Autism

Empowered by Maverix, Biologist Uses RNA-seq to Understand Autism

In Nathaniel Heintz’s molecular biology lab at Rockefeller University, scientists study brain function and dysfunction under a wide array of conditions, from drug abuse to depression. Marian Mellén, a postdoctoral fellow in the lab, is using RNA-seq and other data ...

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