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GTEx Project Community Scientific Meeting

GTEx Project Community Scientific Meeting

July 11, 2016 The 2016 GTEx Project Community Meeting will be held at Stanford University. The meeting will highlight current data sets and types available, various tools being developed for these data types, and results from applying them to the ...

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Genome-wide map of regulatory interactions in the human genome

Genome-wide map of regulatory interactions in the human genome

Increasing evidence suggests that interactions between regulatory genomic elements play an important role in regulating gene expression. Researchers at Stanford University School of Medicine generated a genome-wide interaction map of regulatory elements in human cells (ENCODE tier 1 cells, K562, ...

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iRegulon: From a Gene List to a Gene Regulatory Network

iRegulon: From a Gene List to a Gene Regulatory Network

Identifying master regulators of biological processes and mapping their downstream gene networks are key challenges in systems biology. Researchers at the KU Leuven Center for Human Genetics developed a computational method, called iRegulon, to reverse-engineer the transcriptional regulatory network underlying ...

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Querying the Cancer Transcriptome

from Genetic Engineering News by Richard A. Stein, M.D., Ph.D. The complex and dynamic transcriptional patterns unveiled by the ENCyclopedia of DNA Elements (ENCODE) project, together with the finding that less than 2% of the transcriptional output of the human ...

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STAR: ultrafast universal RNA-seq aligner

To align their large (>80 billon reads) ENCODE Transcriptome RNA-seq dataset, a team of researchers at Cold Spring Harbor Laboratory developed the Spliced Transcripts Alignment to a Reference (STAR) software based on a previously undescribed RNA-seq alignment algorithm that uses ...

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