Tag Archives: ensembl

The Ensembl gene annotation system

rna-seq

The Ensembl gene annotation system has been used to annotate over 70 different vertebrate species across a wide range of genome projects. Furthermore, it generates the automatic alignment-based annotation for the human and mouse GENCODE gene sets. The system is ...

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Impact of gene annotation on RNA-Seq data analysis

RNA-Seq has become increasingly popular in transcriptome profiling. One aspect of transcriptome research is to quantify the expression levels of genomic elements, such as genes, their transcripts and exons. Acquiring a transcriptome expression profile requires genomic elements to be defined ...

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Reduction of Gene Expression Variability from Single Cells to Populations follows Simple Statistical Laws

rna-seq

Recent studies on single cells and population transcriptomics have revealed striking differences in global gene expression distributions. Single cells display highly variable expressions between cells, while cell populations present deterministic global patterns. The mechanisms governing the reduction of transcriptome-wide variability ...

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Ensembl 74 has been released!

rna-seq

from the Ensembl Blog What’s new in e!74? Updated human GENCODE release 19 and mouse GENCODE release M2 gene sets including manual annotation from Havana New assembly patches for human (GRCh37.p13) and mouse (GRCm38.p2) dbSNP Build 138 data for human, mouse and cow ...

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