Tag Archives: gene expression

An RNA-Seq Primer

rna-seq

Pharmacogenomics has revealed compelling genetic signals associated with variability in drug response. Gene expression studies represent an additional approach to identify candidate genes accounting for drug response variability. Researchers from the University of Florida discuss insights that might be gained through analysis of ...

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How to count multi-mapping reads?

rna-seq

RNA-Seq is currently used routinely, and it provides accurate information on gene transcription. However, the method cannot accurately estimate duplicated genes expression. Several strategies have been previously used (drop duplicated genes, distribute uniformly the reads, or estimate expression), but all ...

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