Tag Archives: gene expression

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An evaluation of microRNA alignment techniques

An evaluation of microRNA alignment techniques

Genomic alignment of small RNA (smRNA) sequences such as microRNAs poses considerable challenges due to their short length (∼21 nucleotides [nt]) as well as the large size and complexity of plant and animal genomes. While several tools have been developed ...

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MicroScope: RNA-seq software analysis suite for gene expression heatmaps

MicroScope: RNA-seq software analysis suite for gene expression heatmaps

Researchers at the University of Miami Miller School of Medicine have developed a user-friendly ChIP-seq and RNA-seq software suite for the interactive visualization and analysis of gene expression heatmaps, including integrated features to support: principal component analysis, differential expression analysis, gene ...

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SCell – integrated analysis of single-cell RNA-seq data

SCell – integrated analysis of single-cell RNA-seq data

Analysis of the composition of heterogeneous tissue has been greatly enabled by recent developments in single-cell transcriptomics. Researchers from UCSF have developed SCell, an integrated software tool for quality filtering, normalization, feature selection, iterative dimensionality reduction, clustering and the estimation ...

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