Tag Archives: gene expression

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SCell – integrated analysis of single-cell RNA-seq data

SCell – integrated analysis of single-cell RNA-seq data

Analysis of the composition of heterogeneous tissue has been greatly enabled by recent developments in single-cell transcriptomics. Researchers from UCSF have developed SCell, an integrated software tool for quality filtering, normalization, feature selection, iterative dimensionality reduction, clustering and the estimation ...

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Experimental Design and Power Calculation for RNA-seq Experiments

Experimental Design and Power Calculation for RNA-seq Experiments

(RNA-seq) has become a routine technique in transcriptome analysis, where identifying differential expression (DE) remains a major task. As expression is a stochastic process in nature, the technological improvement in RNA-seq cannot bypass the presence of biological variability. It has ...

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GOexpress – an R/Bioconductor package for the identification and visualisation of robust gene ontology signatures through supervised learning of gene expression data

GOexpress – an R/Bioconductor package for the identification and visualisation of robust gene ontology signatures through supervised learning of gene expression data

Identification of gene expression profiles that differentiate experimental groups is critical for discovery and analysis of key molecular pathways and also for selection of robust diagnostic or prognostic biomarkers. While integration of differential expression statistics has been used to refine ...

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