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Tag Archives: human neural stem cells

Zika virus infected human neural stem cells have unique transcriptomic signatures

June 15, 2016 Leave a comment 3,525 Views

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The single-stranded RNA Flavivirus, Zika virus (ZIKV), has recently re-emerged and spread rapidly across the western hemisphere’s equatorial countries, primarily through Aedes mosquito transmission. While symptoms in adult infections appear to be self-limiting and mild, severe birth defects, such as ...

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Recent RNA-SEQ Pubs

RNA-Seq analysis of interferon inducible p204-mediated network in anti-tumor immunity.
Community Development between Porphyromonas gingivalis and Candida albicans Mediated by InlJ and Als3.
Reciprocal Network between Cancer Stem-Like Cells and Macrophages Facilitates the Progression and Androgen Deprivation Therapy Resistance of Prostate Cancer.
Cross-species inference of long non-coding RNAs greatly expands the ruminant transcriptome.
[Effect of Dishevelled 2 on apoptosis in rheumatoid arthritis fibroblast-like synoviocytes through inhibiting JAK-STAT pathway].
Comparative transcriptomic analysis reveals the mechanism of leech environmental adaptation.

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What is RNA-Seq?

long RNAs are first converted into a library of cDNA fragments through either RNA fragmentation or DNA fragmentation. Sequencing adaptors (blue) are subsequently added to each cDNA fragment and a short sequence is obtained from each cDNA using high-throughput sequencing technology. The resulting sequence reads are aligned with the reference genome or transcriptome, and classified as three types: exonic reads, junction reads and poly(A) end-reads. These three types are used to generate a base-resolution expression profile for each gene. Nat Rev Genet 10(1):57-63 (2009)

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    transIndel – indel detection from DNA and RNA sequencing data

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    Direct RNA sequencing of flu virus genome

    1 day ago
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    Small RNA and degradome sequencing reveals the roles of microRNAs in seed expansion in peanut

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