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Integrating Large-Scale RNA-Seq and CLIP-Seq Datasets Enables Study of lncRNA

Integrating Large-Scale RNA-Seq and CLIP-Seq Datasets Enables Study of lncRNA

Long non-coding RNAs (lncRNAs) are emerging as important regulatory molecules in developmental, physiological, and pathological processes. However, the precise mechanism and functions of most of lncRNAs remain largely unknown. Recent advances in high-throughput sequencing of immunoprecipitated RNAs after cross-linking (CLIP-Seq) ...

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REDItools – Uncovering RNA Editing Sites in Long Non-Coding RNAs

REDItools – Uncovering RNA Editing Sites in Long Non-Coding RNAs

RNA editing is an important co/post-transcriptional molecular process able to modify RNAs by nucleotide insertions/deletions or substitutions. In human, the most common RNA editing event involves the deamination of adenosine (A) into inosine (I) through the adenosine deaminase acting on ...

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The MOuse NOnCode Lung database

The MOuse NOnCode Lung database

The MOuse NOnCode Lung database: mouse long non-coding RNAs (lncRNA) involved in Influenza and SARS-CoV infections The MOuse NOnCode Lung database — MONOCLdb — is an integrative and interactive database designed to retrieve and visualize annotations, expression profiles and functional ...

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RNA: The genome's rising stars

from Nature by Amy Maxmen When Saba Valadkhan lingered in the hallways at conferences, absorbed in discussions about the strands of ‘junk’ DNA that litter the human genome, she was not looking for work. She was consumed with curiosity about ...

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