Tag Archives: microarrays

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Differences in intensity-dependence between RNA-seq and microarrays

Differences in intensity-dependence between RNA-seq and microarrays

Understanding the differences between microarray and RNA-Seq technologies for measuring gene expression is necessary for informed design of experiments and choice of data analysis methods. Previous comparisons have come to sometimes contradictory conclusions. Reseashers from Princeton University suggest that this ...

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Microarray Not Fade Away

Microarray Not Fade Away

Yes, many are attracted to next-generation sequencing, but loyalty to chip-based phenotyping has its rewards, particularly in screens of large sample sets. from Genetic Engineering News – by Lisa Heiden The microarray, the legacy technology for measuring gene expression, will ...

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A defining decade in DNA (and RNA) sequencing

A defining decade in DNA (and RNA) sequencing

from Nature Methods The past decade has seen a transformation, fueled by the availability of NGS platforms, in applications based on generating DNA and RNA sequence. There are more than 50 multiletter-acronym or ‘MLA-seq’ applications for interrogating a wide variety ...

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RNA sequencing – current and prospective uses in metabolic research

RNA sequencing – current and prospective uses in metabolic research

Previous global RNA analysis was restricted to known transcripts in species with a defined transcriptome. Next generation sequencing has transformed transcriptomics by making it possible to analyse expressed genes with an exon level resolution from any tissue in any species ...

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Next Gen Sequencing or Microarray: How to Make the Choice

Next Gen Sequencing or Microarray: How to Make the Choice

from BitsizeBio by Kristin Harper You’re about to start that big project you’ve been dreaming of for years. You’ve identified a potential miracle compound and want to figure out how it affects gene expression. But how are you going to ...

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Multiple Studies Cite Progress toward Quality Transcriptomes

Multiple Studies Cite Progress toward Quality Transcriptomes

from Genetic Engineering News RNA sequencing (RNA-seq), a means of depicting the transcriptome, is being used with increasing frequency to characterize a growing array of conditions—everything from prenatal birth defects to disorders of the elderly. Yet the technique, which is ...

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