Tag Archives: microrna

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Fighting veterinary drug abuse with RNA-Seq

Fighting veterinary drug abuse with RNA-Seq

Worldwide growth and performance-enhancing substances are used in cattle husbandry to increase productivity. In certain countries however e.g., in the EU, these practices are forbidden to prevent the consumers from potential health risks of substance residues in food. To maximize ...

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miTALOS v2 – Analyzing Tissue Specific microRNA Function

miTALOS v2 – Analyzing Tissue Specific microRNA Function

MicroRNAs are involved in almost all biological processes and have emerged as regulators of signaling pathways. Researchers from the German Research Center for Environmental Health show that miRNA target genes and pathway genes are not uniformly expressed across human tissues. To ...

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The dark matter of the cancer genome has been largely neglected

The dark matter of the cancer genome has been largely neglected

Cancer is a disease of the genome caused by oncogene activation and tumor suppressor gene inhibition. Deep sequencing studies including large consortia such as TCGA and ICGC identified numerous tumor-specific mutations not only in protein-coding sequences but also in non-coding ...

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Bioinformatics Resources for MicroRNA Discovery

Bioinformatics Resources for MicroRNA Discovery

Biomarker identification is often associated with the diagnosis and evaluation of various diseases. Recently, the role of microRNA (miRNA) has been implicated in the development of diseases, particularly cancer. With the advent of next-generation sequencing, the amount of data on ...

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Integrating gene expression profiles across different platforms

Integrating gene expression profiles across different platforms

Determining differentially expressed genes (DEGs) between biological samples is the key to understand how genotype gives rise to phenotype. RNA-seq and microarray are two main technologies for profiling gene expression levels. However, considerable discrepancy has been found between DEGs detected ...

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Featured RNA-Seq Job – Research Associate

Featured RNA-Seq Job – Research Associate

REF: 496255 FACULTY OF MEDICINE, DENTISTRY AND HEALTH SCIENCES – UWA CENTRE FOR MEDICAL RESEARCH Laboratory for Cancer Medicine 2 year appointment (further employment subject to funding) Minimum commencing salary for PhD is $88,520 p.a. The University of Western Australia ...

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RNA22 version 2.0 – miRNA-MRE predictions

RNA22 version 2.0 – miRNA-MRE predictions

Researchers at Thomas Jefferson University present rna22, a method for identifying microRNA binding sites and their corresponding heteroduplexes. Rna22 does not rely upon cross-species conservation, is resilient to noise, and, unlike previous methods, it first finds putative microRNA binding sites ...

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