Tag Archives: microrna

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Extending the sRNAome of Apple by Next-Generation Sequencing

Extending the sRNAome of Apple by Next-Generation Sequencing

The global importance of apple as a fruit crop necessitates investigations into molecular aspects of the processes that influence fruit quality and yield, including plant development, fruit ripening and disease resistance. In order to study and understand biological processes it ...

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cGRNB – combinatorial Gene Regulatory Networks Builder

cGRNB – combinatorial Gene Regulatory Networks Builder

We are witnessing rapid progress in the development of methodologies for building the combinatorial gene regulatory networks involving both TFs (Transcription Factors) and miRNAs (microRNAs). There are a few tools available to do these jobs but most of them are ...

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The MicroRNA Expression Signature of Bladder Cancer by Deep Sequencing

The MicroRNA Expression Signature of Bladder Cancer by Deep Sequencing

Current genome-wide microRNA (miRNA) expression signature analysis using deep sequencing technologies can drive the discovery of novel cancer pathways regulated by oncogenic and/or tumor suppressive miRNAs. Researchers at Kagoshima University, Japan determined the genome-wide miRNA expression signature in bladder cancer ...

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Comprehensive annotation of microRNA expression profiles

Comprehensive annotation of microRNA expression profiles

MicroRNAs (miRNAs) regulate many biological processes by post-translational gene silencing. Analysis of miRNA expression profiles is a reliable method for investigating particular biological processes due to the stability of miRNA and the development of advanced sequencing methods. However, this approach ...

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