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gsa4mirna – Integrated gene set analysis for microRNA studies

gsa4mirna – Integrated gene set analysis for microRNA studies

Functional interpretation of miRNA expression data is currently done in a three step procedure: select differentially expressed miRNAs, find their target genes, and carry out gene set overrepresentation analysis Nevertheless, major limitations of this approach have already been described at ...

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Upcoming Webinar – Profiling microRNA from single cells

Upcoming Webinar – Profiling microRNA from single cells

Performing qPCR-based profiling of microRNA from single cells or small cell numbers? Our July 12 webinar will definitely help you get the most out of your precious samples! The webinar focuses on a new, streamlined process for differential expression profiling based on ...

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Recommendations for differential expression analysis and biomarker discovery small RNA-Seq experiments in an age of liquid biopsies

Recommendations for differential expression analysis and biomarker discovery small RNA-Seq experiments in an age of liquid biopsies

Small RNA-Seq has emerged as a powerful tool in transcriptomics, gene expression profiling and biomarker discovery. Sequencing cell-free nucleic acids, particularly microRNA (miRNA), from liquid biopsies additionally provides exciting possibilities for molecular diagnostics, and might help establish disease-specific biomarker signatures. ...

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Fighting veterinary drug abuse with RNA-Seq

Fighting veterinary drug abuse with RNA-Seq

Worldwide growth and performance-enhancing substances are used in cattle husbandry to increase productivity. In certain countries however e.g., in the EU, these practices are forbidden to prevent the consumers from potential health risks of substance residues in food. To maximize ...

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miTALOS v2 – Analyzing Tissue Specific microRNA Function

miTALOS v2 – Analyzing Tissue Specific microRNA Function

MicroRNAs are involved in almost all biological processes and have emerged as regulators of signaling pathways. Researchers from the German Research Center for Environmental Health show that miRNA target genes and pathway genes are not uniformly expressed across human tissues. To ...

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