Tag Archives: next-generation sequencing

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Is Personalized Medicine Here?

Is Personalized Medicine Here?

Clinical application of next-generation sequencing The widespread availability of genomic analysis of tumors in clinical practice has been primarily driven by the advent of next-generation sequencing (NGS). The term “NGS” includes several types of genomic sequencing methodologies, such as targeted ...

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Comprehensive Assessments of RNA-seq by the SEQC Consortium

Comprehensive Assessments of RNA-seq by the SEQC Consortium

Studies on gene expression in response to therapy have led to the discovery of pharmacogenomics biomarkers and advances in precision medicine. Whole transcriptome sequencing (RNA-seq) is an emerging tool for profiling gene expression and has received wide adoption in the ...

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New to RNA-Seq Bioinformatics? Try GeneGazer

New to RNA-Seq Bioinformatics? Try GeneGazer

Next-generation sequencing provides useful information about gene mutations, gene expression, epigenetic modification, microRNA expression, and copy number variations. More and more computing tools have been developed to analyze this large quantity of information. However, to test and find suitable analytical ...

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Measuring the Expression of SINE Retroelements with RNA-Seq

Measuring the Expression of SINE Retroelements with RNA-Seq

The regulation and control of SINE transcription is likely a key process to preserve the physiology and homeostasis of specific tissues and organs. This implies that the analysisof SINE expression is relevant to understand the mechanisms by which these elements ...

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Sequencing Mitochondrial Transcriptomes with RNA-Seq

Sequencing Mitochondrial Transcriptomes with RNA-Seq

Thousands of mitochondrial genomes have been sequenced, but there are comparatively few available mitochondrial transcriptomes. This might soon be changing. High-throughput RNA sequencing (RNA-Seq) techniques have made it fast and cheap to generate massive amounts of mitochondrial transcriptomic data. Here, ...

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Desperately Seq’ing RNA

Desperately Seq’ing RNA

from Genetic Engineering News by Vicki Glaser Next-Generation Sequencing Is Increasingly Making Headway in Clinical Medicine for Diagnostic and Prognostic Purposes It’s early days, but next-generation sequencing (NGS) is increasingly making headway in clinical medicine for diagnostic and prognostic purposes, for ...

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