Tag Archives: next-generation sequencing

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Visualization of nucleotide substitutions in the (micro)transcriptome

Visualization of nucleotide substitutions in the (micro)transcriptome

RNA-related applications of the next-generation sequencing (NGS) technologies require context-specific interpretations: e.g., sequence mismatches may indicate sites of RNA editing, or uneven read coverage often points to mature form of microRNA. Existing visualization tools traditionally show RNA molecules in two ...

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Step by Step – RNA-Seq

Step by Step – RNA-Seq

The introduction of RNA sequencing (RNA-seq), as a direct result of rapid progression of next-generation sequencing technologies, has revolutionized the world of transcriptomics. It enables quantification of the complete set of RNA with all its isoforms in a given cell, ...

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Extending the sRNAome of Apple by Next-Generation Sequencing

Extending the sRNAome of Apple by Next-Generation Sequencing

The global importance of apple as a fruit crop necessitates investigations into molecular aspects of the processes that influence fruit quality and yield, including plant development, fruit ripening and disease resistance. In order to study and understand biological processes it ...

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