Tag Archives: RNA-Seq

Feed Subscription

Optimizing RNA-Seq Mapping with STAR

Optimizing RNA-Seq Mapping with STAR

Sequencing of transcribed RNA molecules (RNA-seq) is an invaluable tool for studying cell transcriptomes at high resolution and depth. RNA-seq datasets typically consist of tens to hundreds of millions of relatively short (30–200 nt) sequence fragments of the original RNA ...

Read More »

Workflow of inter-institutional scRNA-seq big data integration

Workflow of inter-institutional scRNA-seq big data integration

The rapid growth of single-cell RNA-seq studies (scRNA-seq) demands efficient data storage, processing, and analysis. Big-data technology provides a framework that facilitates the comprehensive discovery of biological signals from inter-institutional scRNA-seq datasets. There are several strategies to solve the stochastic ...

Read More »

SinQC – Quality Control of Single-cell RNA-Seq

SinQC – Quality Control of Single-cell RNA-Seq

Single-cell RNA-seq (scRNA-seq) is emerging as a promising technology for profiling cell-to-cell variability in cell populations. However, the combination of technical noise and intrinsic biological variability makes detecting technical artifacts in scRNA-seq samples particularly challenging. Proper detection of technical artifacts ...

Read More »

Modeling of gene regulatory networks from RNA-Seq data

Modeling of gene regulatory networks from RNA-Seq data

Systems biology is a research area which aims to understand living systems as a whole, instead of focusing on single biological entities. Gene regulatory network inference is a systems biology approach which predicts interactions between genes with the help of ...

Read More »

Taking on melanoma, one cell at a time

Taking on melanoma, one cell at a time

from MIT News – Single-cell analysis is a groundbreaking approach now being used across biological fields to explore a common problem: how to study cellular diversity in cell environments with heterogeneous populations. Such diversity can have profound implications for cell ...

Read More »
Scroll To Top