Tag Archives: RNA-Seq

dRNA-Seq – Riboswitch Discovery by Combining RNA-Seq and Genome-Wide Identification of Transcriptional Start Sites

rna-seq

Deep-sequencing technologies applied to RNA have tremendous potential to identify novel transcripts with single-nucleotide resolution. By combining whole-transcript cDNA sequencing (RNA-seq) and genome-wide identification of transcription start sites (dRNA-seq), it is possible to characterize long 5′-untranslated regions potentially endowed with ...

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Disease Biomarker Query from RNA-Seq Data

rna-seq

As a revolutionary way to unveil transcription, RNA-Seq technologies are challenging bioinformatics for its large data volumes and complexities. A large number of computational models have been proposed for differential expression (DE) analysis and normalization from different standing points. However, ...

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Most Read Blog Posts – October 2014

rna-seq

A Comparison of Next Generation Sequencing Technologies for Transcriptome Assembly 1,502 Views Analysis of the RNA content of the exosomes derived from blood serum and urine and its potential as biomarkers 1,471 Views Choosing a next-generation sequencing pipeline 1,284 Views ...

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piPipes – a set of pipelines for piRNA and transposon analysis via small RNA-seq, RNA-seq, degradome- and CAGE-seq, ChIP-seq and genomic DNA sequencing

PIWI-interacting RNAs (piRNAs), 23-36 nt small silencing RNAs, repress transposon expression in the metazoan germ line, thereby protecting the genome. Although high-throughput sequencing has made it possible to examine the genome and transcriptome at unprecedented resolution, extracting useful information from ...

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Enabling large-scale next-generation sequence assembly with Blacklight

rna-seq

A variety of extremely challenging biological sequence analyses were conducted on the XSEDE large shared memory resource Blacklight, using current bioinformatics tools and encompassing a wide range of scientific applications. These include genomic sequence assembly, very large metagenomic sequence assembly, ...

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Post-doc Postions Available – Texas State University

One or two postdoctoral positions are available immediately in Oncinfo Lab, Department of Computer Science at Texas State University. Position description The successful candidates will contribute to development and application of cutting edge computational methods to analyze RNA-seq and other ...

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