Tag Archives: RNA-Seq

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Roche to Reorganize Sequencing Business

Measures aim to ensure sustained success in a fast-changing market environment Roche today announced changes to the management and set-up of its life-science business. The Applied Science Business Area will be dissolved and its portfolio of products integrated within Roche’s ...

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RNA sequencing of cancer reveals novel splicing alterations

Breast cancer transcriptome acquires a myriad of regulation changes, and splicing is critical for the cell to “tailor-make” specific functional transcripts. Researchers at The George Washington University systematically revealed splicing signatures of the three most common types of breast tumors ...

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RNA-seq identifies a super-long intergenic transcript

RNA transcripts are generally classified into polyA-plus and polyA-minus subgroups due to the presence or absence of a polyA tail at the 3′ end. Even though a number of physiologically and pathologically important polyA-minus RNAs have been recently identified, a ...

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Accurate detection of differential RNA processing

Deep transcriptome sequencing (RNA-Seq) has become a vital tool for studying the state of cells in the context of varying environments, genotypes and other factors. RNA-Seq profiling data enable identification of novel isoforms, quantification of known isoforms and detection of ...

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SeqGSEA – Gene Set Enrichment Analysis of RNA-Seq Data

SeqGSEA – Gene Set Enrichment Analysis of RNA-Seq Data

Transcriptome sequencing (RNA-Seq) has become a key technology in transcriptome studies because it can quantify overall expression levels and the degree of alternative splicing for each gene simultaneously. Many methods and tools, including quite a few R / Bioconductor packages, ...

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