Tag Archives: transcriptome sequencing

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An integrative method to normalize RNA-Seq data

An integrative method to normalize RNA-Seq data

Transcriptome sequencing is a powerful tool for measuring gene expression, but as well as some other technologies, various artifacts and biases affect the quantification. In order to correct some of them, several normalization approaches have emerged, differing both in the ...

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A comprehensive metatranscriptome analysis pipeline

A comprehensive metatranscriptome analysis pipeline

Next generation sequencing (NGS) technologies can be applied in complex microbial ecosystems for metatranscriptome analysis by employing direct cDNA sequencing, which is known as RNA sequencing (RNA-seq). RNA-seq generates large datasets of great complexity, the comprehensive interpretation of which requires ...

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A Review of Computational Tools in microRNA Discovery

Since microRNAs (miRNAs) were discovered, their impact on regulating various biological activities has been a surprising and exciting field. Knowing the entire repertoire of these small molecules is the first step to gain a better understanding of their function. High ...

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RNA 'Transcriptome' Sequenced in Immune Cells

from Bioscience Technology.com When studying any kind of population — people or cells — averaging is a useful, if flawed, form of measurement. According to the US Census Bureau, the average American household size in 2010 was 2.59. Of course, ...

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