Tag Archives: transcriptomics

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Buliding a Human from Transcriptional Profiles

Buliding a Human from Transcriptional Profiles

The manual for human development is written in the genetic code of our DNA. Our genes encode the instructions to make specific types of molecules that are needed to either build the human body or to control its day-to-day operations. ...

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Single cell transcriptomics of the human endocrine pancreas

Single cell transcriptomics of the human endocrine pancreas

Human pancreatic islets consist of multiple endocrine cell types. To facilitate the detection of rare cellular states and uncover population heterogeneity, UPENN School of Medicine researchers performed single-cell RNA-sequencing on islets from multiple deceased organ donors, including children, healthy adults, ...

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Fighting veterinary drug abuse with RNA-Seq

Fighting veterinary drug abuse with RNA-Seq

Worldwide growth and performance-enhancing substances are used in cattle husbandry to increase productivity. In certain countries however e.g., in the EU, these practices are forbidden to prevent the consumers from potential health risks of substance residues in food. To maximize ...

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The potential of single-cell transcriptomics in plants

The potential of single-cell transcriptomics in plants

Single-cell RNA-seq works as efficiently in plant cells as in animal cells. Noise profiles are well understood and an early set of analytical approaches is now capable of extracting information not previously possible in pooled samples. The biggest technical challenges ...

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BBBomics – Human Blood Brain Barrier Transcriptomics Hub

BBBomics – Human Blood Brain Barrier Transcriptomics Hub

Blood-brain barrier (BBB) is a monolayer of endothelial cells that line brain capillaries. The BBB protects brain by blocking the entry of harmful substances from blood and shielding the brain from peripheral fluctuations in hormones, fatty acids, and electrolytes. In ...

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