The Emergence of lncRNA

lncRNA lncRNA Database
Most (~75%) of the catalogued lncRNAs are from mammals, for which more transcriptomic data is available and which have been more intensively studied, but lncRNAs from vertebrates to single-celled eukaryotes have been included. In addition, lncRNAdb has links to the UCSC Genome Browser for visualization and NRED (ncRNA Expression Database) for expression information from a variety of sources.

Macro lncRNAs: A new layer of cis-regulatory information in the mammalian genome.
Guenzl P, Barlow D.
RNA Biol. 2012 Jun 1;9(6). [Epub ahead of print]

Long Noncoding RNA: Its Physiological and Pathological Roles.
Yan B, Wang Z.
DNA Cell Biol. 2012 May 21. [Epub ahead of print]

Regulatory long non-coding RNA and its functions.
Huang Y, Liu N, Wang JP, Wang YQ, Yu XL, Wang ZB, Cheng XC, Zou Q.
J Physiol Biochem. 2012 Apr 26. [Epub ahead of print]

Emerging functional and mechanistic paradigms of mammalian long non-coding RNAs.
Moran VA, Perera RJ, Khalil AM.
Nucleic Acids Res. 2012 Apr 5. [Epub ahead of print]

Exploring long non-coding RNAs through sequencing.
Atkinson SR, Marguerat S, Bähler J.
Semin Cell Dev Biol. 2012 Apr;23(2):200-5. Epub 2011 Dec 20.

The Emergence of lncRNAs in Cancer Biology.
Prensner JR, Chinnaiyan AM.
Cancer Discov. 2011 Oct;1(5):391-407.

Long noncoding RNAs and human disease.
Wapinski O, Chang HY.
Trends Cell Biol. 2011 Jun;21(6):354-61. Epub 2011 May 6.

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  1. Darya Vanichkina

    The link to the database is: and

    The manuscript in which the database is described is:

    lncRNAdb: a reference database for long noncoding RNAs
    Paulo P. Amaral, Michael B. Clark, Dennis K. Gascoigne, Marcel E. Dinger* and John S. Mattick

    Also, you have omitted posting links to the research of John Mattick and John Rinn, both of whom are pioneers in the field who have contributed immensely to understanding the roles these molecules play in the cell. Anyone who would like to enter this field should definitely consider their work.

  2. Everything is very open and very clear explanation of issues. Your website is very useful. Thanks for sharing.

  3. ChIPBase( constructed expression profiles of lncRNAs and mRNAs from RNA-Seq data across 22 human normal tissues.

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