RNA interference (RNAi) is known to play an important part in defense against viruses in a range of species. Second-generation sequencing technologies allow us to assay these systems and the small RNAs that play a key role with unprecedented depth. However, scientists need access to tools which can condense, analyse and display the resulting data. Here we present viRome, a package for R that takes aligned sequence data and produces a range of essential plots and reports.
Availability: viRome is released as a package for R available for both Windows and Linux http://virome.sf.net
Supplementary Information: Additional information and a tutorial is available on the ARK-Genomics website: http://www.ark-genomics.org/bioinformatics/virome.
- Watson M, Schnettler E, Kohl A. (2013) viRome: an R package for the visualization and analysis of viral small RNA sequence datasets. Bioinformatics [Epub ahead of print]. [abstract]