The development of single cell RNA-sequencing (scRNA-seq) technologies has greatly contributed to deciphering the tumor microenvironment (TME). An enormous amount of independent scRNA-seq studies have been published representing a valuable ...
Read More »RNA-SEQ NEWS
Correspondence analysis for dimension reduction, batch integration, and visualization of single-cell RNA-seq data
Effective dimension reduction is essential for single cell RNA-seq (scRNAseq) analysis. Principal component analysis (PCA) is widely used, but requires continuous, normally-distributed data; therefore...
Read More »Mutant KRAS signaling drives alternative splicing in lung cancer cells
What eventually becomes a graduate student’s PhD thesis work is rarely the project they initially pursued. However, in rare cases like with recent...
Read More »Single cell RNA-sequencing identifies cause for loss of smell in long COVID patients
As the pandemic continues, millions of people in the U.S. are facing long COVID, a complex, poorly understood chronic illness with symptoms that...
Read More »ESPRESSO – robust discovery and quantification of transcript isoforms from error-prone long-read RNA-seq data
Long-read RNA sequencing (RNA-seq) holds great potential for characterizing transcriptome variation and full-length transcript isoforms, but the relatively high error rate of current long-read sequencing...
Read More »Single-cell RNA sequencing reveals how Huntington’s disease affects different neurons
A new study identifies cells that are the most vulnerable within a brain structure involved in mood and movement. In patients with Huntington’s...
Read More »PAIso-seq reveals how poly(A)-tail-mediated remodeling of maternal mRNA controls start of life
Human development starts from the fertilization of a fully matured oocyte. Oocyte maturation, fertilization, and early embryo development before...
Read More »Jobs
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Post-doc position available – Bioinformatics
A Bioinformatics/Genomics postdoctoral fellow position is available immediately in the Department of Pathology at Harvard Medical School/Beth Israel Deaconess Medical Center to study microRNAs in...
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Featured RNA-Seq Job – CCG Single-Cell/-Nucleus Sequencing Group Leader, Scientist II
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Funded PhD Project – Redrawing cancer immune transcriptomic maps with Nanopore sequencing
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Post-doc position available – data-driven biology
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Featured RNA-Seq Job – Single-Cell/-Nucleus Sequencing Group Leader
Industry News
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Singleron launches single cell eQTL analysis as part of their sequencing service
A new bioinformatic pipeline to investigate single cell eQTL analysis is now offered in the sequencing service from Singleron Biotechnologies. Bioinformatic experts at Singleron Biotechnologies, a leader in single cell ...
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Qlucore announces software upgrade to facilitate improved single cell data analysis
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Jumpcode Genomics Joins 10X Genomics’ Compatible Partner Program
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CD Genomics RNA-Solutions Platform Unveils m7G MeRIP Sequencing for Scientific Research
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Veracyte’s RNA sequencing-based Afirma Genomic Sequencing Classifier test performs just as well – and on some measures better – in clinical practice