Monthly Archives: December 2015

Combining RNA-Seq Proteogenomics and Global Post-Translational Modification (G-PTM) Search Strategy Reveals Human Proteomic Variation

Mass spectrometry-based proteomic analysis underestimates proteomic variation due to the absence of variant peptides and posttranslational modifications (PTMs) from standard protein databases. Each individual carries thousands of missense mutations that lead to single amino acid variants, but these are missed ...

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