From News-Medical.net by Sarah Moore
The collection of RNA molecules in a cell, known as the transcriptome, holds the key to a wealth of useful information. It can tell us where genes are turned on and off, as well as uncovering to what extent the gene is active. RNA sequencing is a method that allows scientists to look into the transcriptome of a cell and acquire this information. Assays that carry out RNA sequencing have advantages over previous methods of investigating gene expression such as Sanger sequencing and microarray-based methods because they provide a higher resolution and greater coverage of the transcriptome. In addition to gaining insight into the gene expression within cells of tissues and organs, these assays can identify novel transcripts and find alternatively spliced genes, as well as uncovering allele-specific expression.
(read more…)
From News-Medical.net by Sarah Moore
The collection of RNA molecules in a cell, known as the transcriptome, holds the key to a wealth of useful information. It can tell us where genes are turned on and off, as well as uncovering to what extent the gene is active. RNA sequencing is a method that allows scientists to look into the transcriptome of a cell and acquire this information. Assays that carry out RNA sequencing have advantages over previous methods of investigating gene expression such as Sanger sequencing and microarray-based methods because they provide a higher resolution and greater coverage of the transcriptome. In addition to gaining insight into the gene expression within cells of tissues and organs, these assays can identify novel transcripts and find alternatively spliced genes, as well as uncovering allele-specific expression.
(read more…)
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From News-Medical.net by Sarah Moore
The collection of RNA molecules in a cell, known as the transcriptome, holds the key to a wealth of useful information. It can tell us where genes are turned on and off, as well as uncovering to what extent the gene is active. RNA sequencing is a method that allows scientists to look into the transcriptome of a cell and acquire this information. Assays that carry out RNA sequencing have advantages over previous methods of investigating gene expression such as Sanger sequencing and microarray-based methods because they provide a higher resolution and greater coverage of the transcriptome. In addition to gaining insight into the gene expression within cells of tissues and organs, these assays can identify novel transcripts and find alternatively spliced genes, as well as uncovering allele-specific expression.
(read more…)
Related Posts
Worm’s radical transformation shows metamorphosis can change the functions of cells
RNA sequencing reveals functional chimeric mRNAs in mammalian immunity
Atlas of the brain’s striatum could guide researchers to new drug treatments
Immune cells offer insights on billion-dollar virus
A functionally integrated cross-tissue alternative splicing program during short-term calorie restriction
Dietary oxidized plant sterol shifts macrophage state to fuel aortic inflammation
Unlocking the past – new method helps gain insights into old tissue
Novel AI model trained on RNA-Seq data accurately detects key gene mutations and predicts biomarkers across 32 cancer types
Transcriptomic aging clock reveals age-related molecular patterns in opioid dependence
RNA sequencing helps predict stem cell transplant benefit in pediatric AML
Protein ‘switch’ determines whether liposarcoma cells will become aggressive
Precursor tRNAs sense temperature changes: heat stress-induced capped pre-tRNAs suppress protein synthesis
Ketamine increases neuroplasticity in female mice but not in males
Somatic mutations linked to vascular damage in progeria
Scientists map dormant cancer cells’ hideouts, opening new targets for treatment
Soluble signals released by neighboring cells direct how the human kidney is built
Genetics influence how cancer arises – and how it evolves
RNA-based testing uncovers extraordinary diversity in mutations driving lung cancer
Study offers new insights into why ex-smokers remain at elevated risk of lung disease
Learning the grammar of gene regulation
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