Are Your RNA-Seq Data Replicable?

from “Big data studies come with replication challenges” by Tina Hesman Saey


FOOL’S GOLD As researchers pan for nuggets of truth in big data studies, how do they know they haven’t discovered fool’s gold?

It has taken more than 15 years for microarray technology to develop enough so that scientists can easily compare their data. Researchers conducting other types of big data studies (such as RNA-Seq) hope that the lessons learned from more mature fields will help catapult them past pitfalls to safer ground where data can be trusted. With data shooting from sequencing machines and other high-throughput laboratory equipment like water from a fire hose, it has never been more important that researchers learn what it takes to make their results as reliable as possible.

(read more at Science News)


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