The selection of a first-line chemotherapy drug to treat many types of cancer is often a clear-cut decision governed by standard-of-care protocols, but...

Advaita Bioinformatics has announced a new release of iPathwayGuide, the world’s most advanced RNA-seq and gene expression analysis software. This release includes unprecedented gene network analysis and literature mining capabilities. The newly added...

In RNA-seq differential expression analysis, investigators aim to detect those genes with changes in expression level across conditions, despite technical and biological variability in the observations. A common task is to accurately estimate the effect...

New findings add to growing evidence that previously dismissed "junk DNA" actually produces RNA molecules with important regulatory functions Scientists have identified an RNA molecule with broad powers to regulate the body's inflammatory...

Karolinska Institutet researchers have developed FuSeq, a fast and accurate method to discover fusion genes based on quasi-mapping to quickly map the reads, extract initial candidates from split reads and fusion equivalence classes of mapped reads, and...

Stanford scientists and their collaborators have identified two key genes responsible for the rapid growth of deer antlers. They hope their insights...

Illumina and Pacific Biosciences today announced they have signed an agreement for Illuminato acquire Pacific Biosciences at a price of $8.00 per Pacific Biosciences share in an all-cash transaction. This price represents a premium of ...

Extracellular microRNAs (miRNAs) and other small RNAs are implicated in cellular communication and may be useful as disease biomarkers. UCSF researchers systematically compared small RNAs in 12 human biofluid types using RNA sequencing...

In-depth analysis sorts cells from the cerebral cortex into 133 types, lays groundwork to explore function undefined. Neuroscientists used a new, gene-based classification of mouse brain cell types and additional...

RNA polymerase II (Pol II) plays an essential role in gene expression. We used plant native elongating transcript sequencing and global run-on sequencing to profile nascent RNAs genome wide in Arabidopsis. Researchers at Guangzhou University found...