Single-cell transcriptomic approaches have revolutionised the study of complex biological systems, with the routine measurement of gene expression in thousands of cells enabling...
Read More »Single-nucleus RNA sequencing reveals why a specific type of neuron dies in Parkinson’s disease
Parkinson’s disease is marked by the death of dopamine-producing neurons in the brain — specifically in the substantia nigra, a structure...
Read More »Single Cell Analysis Boot Camp: Systems Biology Methods for Analysis of Single Cell RNA-Seq
The Single Cell Analysis Boot Camp is a two-day intensive training of seminars and hands-on analytical sessions to launch students on a path...
Read More »Single-cell RNA sequencing reveals the individual immune cells inside the plaque that causes life-threatening heart attacks
Through single-cell RNA sequencing, a research group has successfully illuminated the characteristics of Myeloid immune cells in coronary plaque, which causes acute coronary syndrome (this term includes...
Read More »NEAT-seq – simultaneous profiling of intra-nuclear proteins, chromatin accessibility and gene expression in single cells
Stanford University School of Medicine researchers have developed NEAT-seq (sequencing of nuclear protein epitope abundance, chromatin accessibility and the transcriptome in single cells), enabling...
Read More »Fluent BioSciences expands access to industry’s most flexible and scalable technology (PIPseq™) to enable sensitive single-cell transcriptome analysis in any laboratory
Fluent BioSciences, a biotechnology company focused on making single-cell analysis simple and accessible to every researcher, announced expanded early access to two new products for 3′ single-cell RNA analysis...
Read More »New tool integrates microbiome and host genetic sequencing analysis
A new software tool makes it easier to study relationships between a host, its microbiome and pathogens like HIV or SARS-CoV-2. Researchers...
Read More »Stereo-seq enables first panoramic spatial atlases of life
In a series of studies published in Cell Press journals, STOC members used the spatially resolved transcriptomics technology Stereo-seq, developed by BGI-Research, to produce spatiotemporal cellular...
Read More »New open-source software automates RNA analysis to speed up research and drug development
“Pytheas” app created by a team at Scripps Research allows scientists to identify and quantify modified RNA molecules more easily than ever. Scientists at Scripps Research have unveiled a new software tool for studying RNA (ribonucleic acid) molecules, which have ...
Read More »A comparison of strategies for generating artificial replicates in RNA-seq experiments
Due to the overall high costs, technical replicates are usually omitted in RNA-seq experiments, but several methods exist to generate them artificially...
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