Single-cell and single-embryo RNA sequencing
Single-cell and single-embryo RNA sequencing enables detailed analysis of gene expression and cell identity during the earliest stages of embryonic development...
RNA sequencing reveals functional chimeric mRNAs in mammalian immunity
Direct RNA sequencing revealed thousands of chimeric mRNAs in mammalian cells, uncovering previously unknown proteins with roles in immunity, inflammation, and potential drug discovery...
Deep learning improves microRNA target prediction from sequence
MicroRNAs, or miRNAs, are small RNA molecules that help control gene expression. They work by guiding Argonaute proteins to specific RNA targets, where they can reduce the production of proteins from those genes. Predicting which RNAs a miRNA will ...
New Johns Hopkins Study Identifies Pervasive RT-qPCR Artifact in CRISPR Knockdown Studies and How UltraMarathonRT® Solves It
Guide RNAs from RNA-targeting CRISPR systems remain bound to their target mRNA after total RNA preparations and suppress conventional reverse transcription. uMRT's strand-displacing reverse transcriptase restores accurate knockdown quantification. RNAConnect, a life science company providing next- generation tools to ...
Atlas of the brain’s striatum could guide researchers to new drug treatments
A new study reveals insights into populations of neurons affected by Huntington’s disease, schizophrenia, addiction, and other disorders. A region of the brain called the striatum is critical for many cognitive and motor functions, including decision-making, control of movement, ...
scLS – a computationally efficient differentially expressed gene detection algorithm
The proposed algorithm enables pseudotime-based dynamics without the need for explicit regression models or branch assignment Single-cell RNA sequencing (scRNA-seq) is a method to measure gene expression of individual cells, allowing observation of various cellular processes, including cell differentiation, ...
Lexogen Expands NGS Services with GCLP-Compliant Workflows
Lexogen, a specialist in RNA sequencing technologies and next-generation sequencing services, announces the availability of designated NGS service workflows operated in compliance with the principles of the World Health Organization's Good Clinical Laboratory Practice guidance. The offering is designed for clinical research and clinical-trial projects requiring ...
Spatial mapping of RNA turnover kinetics in the mouse brain
Gene expression is often described by measuring how much RNA is present in a cell at a given moment. But RNA levels are constantly changing as new molecules are produced and older ones are broken down. Measuring both processes ...
Immune cells offer insights on billion-dollar virus
Whiteleg shrimp studies examine key organs and pinpoint genes linked to virus response. Studies have shed light on a disease that has caused billion-dollar losses in a key commercial seafood species. Insights into the immune system of the Pacific whiteleg shrimp, ...
SPIDER improves spatial transcriptomics data using single-cell RNA sequencing
Spatial transcriptomics is a powerful technology that allows researchers to measure gene activity while preserving information about where cells are located within a tissue. Unlike traditional RNA sequencing, which can lose this spatial information when tissue is broken apart, ...
RNA-Seq Products & Services
Most Shared Posts
- Upcoming Conference – The Festival of Genomics & Biodata
- Gene trajectory inference for single-cell data by optimal transport metrics
- Upcoming Workshop – Advanced Topics in Single Cell RNA-Seq Analysis: Multiomics ATAC-Seq & RNA-Seq
- BAP-seq – bioorthogonal masked acylating agents for proximity-dependent RNA labelling
- Single-cell RNA-seq of the rare virosphere reveals the native hosts of giant viruses in the marine environment
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