Author Archives: RNA-Seq Blog

StructureImpute – A deep learning method for recovering missing signals in transcriptome-wide RNA structure profiles from probing experiments


Sequencing-based RNA structure probing can generate transcriptome-wide profiles of RNA secondary structures. Sufficient structural coverage is needed to obtain unbiased insights about RNA structures and functions, yet probing methods often yield uneven coverage, with missing structural scores across many transcripts. ...

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