The availability of low-cost small-factor sequencers, such as the Illumina MiSeq, MiniSeq, or iSeq, have paved the way for democratizing genomics sequencing, providing researchers in minority universities with...

Patient specific stem cell-derived motor neurons stained for the neuronal marker III-Tubulin (green) and the ALS-implicated protein TDP-43 (magenta). In this study, the authors determined that TDP-43...

Start Application Scientist I – Computation, Analysis & Biovisualization The Allen Institute for Brain Science, located in Seattle, Washington, has an ambitious, multi-disciplinary effort to reverse engineer complex neural circuits by understanding their diverse cellular parts. A key component of this ...

Next-generation sequencing has evolved into a powerful diagnostic tool helping thousands get answers to the most challenging disease diagnoses. Even with today’s newest equipment, many...

Description: The postdoctoral researcher would integrate, asap, the Laboratory of Evolutionary Genetics and Ecology of Karine Van Doninck at...

Huntington’s disease (HD) is characterized by hypomyelination and neuronal loss. To assess the basis for myelin loss in HD, we generated bipotential glial progenitor cells (GPCs) from human embryonic stem cells (hESCs) derived from mutant Huntingtin (mHTT) embryos or normal ...

The usual analysis of RNA sequencing (RNA-seq) reads is based on an existing reference genome and annotated gene models. However, when a...

28 Feb 2019 at 11:00 (GMT -06:00) Jonathan Göke – Senior Research Scientist (PI) Genome Institute of Singapore (A*STAR) The ability of RNA-sequencing to generate a high-dimensional, quantitative readout...

Description Our lab is interested in transcriptome and epigenetic changes that occur in a time-dependent manner during pregnancy and how those can influence autoimmune disease. We are seeking a highly motivated and creative postdoctoral fellow to examine changes in coding ...

Circular RNAs are an emerging class of transcript isoforms created by unique back splicing of exons to form a closed covalent circular structure. While...