Making sense of childhood growth Background Dr Adam Stevens, is a human development systems biologist working in Professor Peter Clayton’s group at the UK’s University of Manchester. In addition to industrially-funded and commercially-sensitive research into drug responses, Dr. Stevens and ...
Read More »RNASeqExpressionBrowser – A web interface to browse and visualize high-throughput expression data
RNA-seq techniques generate massive amounts of expression data. Several pipelines (e.g. Tophat and Cufflinks) are broadly applied to analyse these data sets. However, accessing and handling the analytical output remains challenging for non-experts. Researchers at the Helmholtz Center Munich now ...
Read More »Upcoming Webinar – The Hows and Whys of RNA-Seq
Date: Thursday, May 22nd Time: 11AM PST · 2PM EST Duration: 45 minutes Title: The Hows and Whys of RNA-Seq Whether you’re a seasoned researcher or a transcriptomics newbie, an in-depth look at the complexities of RNA-seq analysis can be ...
Read More »RNAbrowse: RNA-Seq De Novo Assembly Results Browser
Transcriptome analysis based on a de novo assembly of next generation RNA sequences is now performed routinely in many laboratories. The generated results, including contig sequences, quantification figures, functional annotations and variation discovery outputs are usually bulky and quite diverse. ...
Read More »De Novo Transcriptome Assembly and Analyses of Gene Expression during Photomorphogenesis in Diploid Wheat Triticum monococcum
Triticum monococcum (2n) is a close ancestor of T. urartu, the A-genome progenitor of cultivated hexaploid wheat, and is therefore a useful model for the study of components regulating photomorphogenesis in diploid wheat. In order to develop genetic and genomic ...
Read More »A multi-Poisson dynamic mixture model to cluster developmental patterns of gene expression by RNA-seq
Dynamic changes of gene expression reflect an intrinsic mechanism of how an organism responds to developmental and environmental signals. With the increasing availability of expression data across a time-space scale by RNA-seq, the classification of genes as per their biological ...
Read More »compcodeR – an R package for benchmarking differential expression methods for RNA-seq data
compcodeR is an R package for benchmarking of differential expression analysis methods, in particular methods developed for analyzing RNA-seq data. The package provides functionality for simulating realistic RNA-seq count data sets, an interface to several of the most commonly used ...
Read More »Featured RNA-Seq Job – Sr Manager Marketing Development NGS RNA-Seq
Hiring Company Industry: Biotech/Pharma Number of Employees: 1 – 100 Employees Total Compensation: Doe Base Salary: Doe Location: South San Francisco, CA Job Description Senior Manager/ Manger Market Development, NGS RNA-Seq The Senior Manager/ Manager of Market Development ...
Read More »Integrated In Silico Analysis of NGS Prostate Cancer Data via High – Resolution RNA – Seq Analysis
Sandeep Sanga , Antoaneta Vladimirova, Aubree Hoover Ingenuity Systems, CLC Bio The goal: To get novel insights into the mechanisms of prostate adenocarcinoma by leveraging next generation sequencing (NGS) data, particularly human transcriptome data, through in silico data analysis and ...
Read More »CFIm25 links alternative polyadenylation to glioblastoma tumour suppression
The global shortening of messenger RNAs through alternative polyadenylation (APA) that occurs during enhanced cellular proliferation represents an important, yet poorly understood mechanism of regulated gene expression. The 3′ untranslated region (UTR) truncation of growth-promoting mRNA transcripts that relieves intrinsic ...
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