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The Neuroscience Monoclonal Antibody Sequencing Initiative (NeuroMabSeq) is a concerted effort to determine and make publicly available hybridoma-derived sequences of monoclonal antibodies (mAbs) valuable to neuroscience research. Over 30 years of research and development efforts including those at the UC ...

Neurons stochastically generated up to eight different versions of a protein-regulating neurotransmitter release, which could vary how...

Qlucore is a leading provider of new generation bioinformatics software for research, and precision and companion diagnostics. Founded in 2007 by scientists inspired to simplify the process of data analysis for researchers, the company has worked with a number of ...

NVIGEN, a leading provider of modern nanoparticle solutions to empower revolutionary personalized healthcare, announces its new application in RNA sequencing (RNAseq) that promises to transform our...

New research in model protocells reveals naturally occurring chemical modifications to RNA molecules help them properly fold into functional structures To investigate potential early steps taken by the first...

Novel methods that combine single cell RNA-seq with CRISPR screens enable high-throughput characterization of transcriptional changes caused by genetic perturbations. Dedicated software is however lacking to annotate CRISPR guide RNA (gRNA) libraries and associate them with single cell transcriptomes. Here, ...

Investigators led by Kathleen Green, PhD, the Joseph L. Mayberry, Sr., Professor of Pathology and Toxicology, have discovered novel intercellular “crosstalk” between epidermal keratinocytes and melanoma cells that promote cancer growth and...

The ever-growing compendium of genetic variants associated with human pathologies demands new methods to study genotype-phenotype relationships in complex tissues in a high-throughput manner...

Transposable elements (TEs) serve as both insertional mutagens and regulatory elements in cells, and their aberrant activity is increasingly...

The transcriptional intermediates of RNAs fold into secondary structures with multiple regulatory roles, yet the details of such cotranscriptional RNA...