A new bioinformatic pipeline to investigate single cell eQTL analysis is now offered in the sequencing service from Singleron Biotechnologies. Bioinformatic experts at Singleron Biotechnologies, a leader in single cell sequencing, have developed a new single cell eQTL analysis workflow ...
Read More »Mutant KRAS signaling drives alternative splicing in lung cancer cells
What eventually becomes a graduate student’s PhD thesis work is rarely the project they initially pursued. However, in rare cases like with recent...
Read More »Single cell RNA-sequencing identifies cause for loss of smell in long COVID patients
As the pandemic continues, millions of people in the U.S. are facing long COVID, a complex, poorly understood chronic illness with symptoms that...
Read More »Single-cell RNA sequencing reveals how Huntington’s disease affects different neurons
A new study identifies cells that are the most vulnerable within a brain structure involved in mood and movement. In patients with Huntington’s...
Read More »PAIso-seq reveals how poly(A)-tail-mediated remodeling of maternal mRNA controls start of life
Human development starts from the fertilization of a fully matured oocyte. Oocyte maturation, fertilization, and early embryo development before...
Read More »RNA sequencing study reveals new molecular associations with obesity
New research from the Department of Biomedical Informatics (DBMI) at the University of Colorado School of Medicine has identified 45 genes whose gene expression is associated with body mass...
Read More »The NGS Race Is On: Souped-Up Sequencers Vie for Frontrunner Status
New and better instruments, from aspiring and established companies alike, made 2022 a banner year for next-generation sequencing...
Read More »A new sequencing technique achieves high-quality results from small volumes of frozen tumor specimens archived in biobanks
Columbia researchers invent a technique to study cancer tissues archived in biobanks, increasing the number and variety of tumor samples available for scientific analysis and advancing the discovery of...
Read More »Single-cell transcriptomics of peripheral blood in the aging mouse
Compositional and transcriptional changes in the hematopoietic system have been used as biomarkers of immunosenescence and aging. In this study...
Read More »Researchers produce first-ever toolkit for RNA sequencing analysis using a ‘pantranscriptome’
Analyzing a person’s gene expression requires mapping their RNA landscape to a standard reference to gain insight into the degree to which...
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