Commentary

scRNA-seq has become a widespread technique within the life sciences but analysis of the data has previously required an in-depth understanding of complex bioinformatics techniques...

A new method that analyzes how individual immune cells react to the bacteria that cause tuberculosis could pave the way for new vaccine strategies against this deadly disease, and provide insights into fighting other infectious diseases around the world. The ...

St. Jude Children’s Research Hospital study highlights the power of comprehensive whole genome, whole exome and RNA sequencing to...

Researchers from HSE University have discovered nucleotide sequences characteristic of microRNA isoforms (microRNAs with errors). The discovery will help predict errors in microRNA behaviour and...

Tumor heterogeneity—the complex microenvironment of different cell subpopulations within a single tumor—remains a major challenge...

Researchers at the University of Michigan Medical School, used Bru-seq and BruChase-seq RNA sequencing to investigate the efficiency of splicing across different human cell types. The results were surprising in that the splicing process appears to...

For most organisms, DNA sequences are available, but the complete RNA sequences are not. Here, we call for technologies to sequence full-length RNAs...

A subset of fibroblasts located in small foci of tissue on the edges of extensive scarring produce a protein that protects against cell aging. Single-cell RNA...

Faculty members from the University of Tennessee Health Science Center have led the development of PubSeq, a global digital data repository of COVID-19 RNA sequences. PubSeq is open to all interested...

What’s stressing out bumblebees? To find out, York University scientists used next-generation sequencing to look deep inside bumblebees for evidence of pesticide exposure, including...