Therapeutics based on messenger RNA, or mRNA, can potentially treat a wide range of maladies, including cancer, genetic diseases, and as the world..
Read More »Researchers develop online portal to show how biases in RNA sequences affect gene expression
A recent publication from researchers at the University of Kentucky explains the importance of identifying and understanding how differences...
Read More »scRNA-Seq draws a a roadmap to future personalized medicine for heart defects that develop before birth
A team of investigators from Texas Heart Institute, Texas Children’s Hospital and Baylor College of Medicine uncovered new insights into the mechanisms underlying the progression of congenital heart...
Read More »Single-cell map of heart failure suggests possible therapeutic targets
By studying individual cardiac cells from heart failure patients, researchers have identified molecular signatures that point to biological mechanisms of...
Read More »RNA sequencing reveals changed gene expression after heart surgery extends cardiomyocyte regeneration
While lower vertebrates can repair their adult hearts after a heart attack, mammals — including humans — cannot. The ability to regenerate dead muscle tissue in mammalian hearts disappears just a few...
Read More »Amphioxus sequencing gives insight on vertebrate evolution
Vertebrate evolution was accompanied by two rounds of whole genome duplication followed by functional divergence in terms of regulatory circuits and gene expression patterns. As a basal and slow...
Read More »Single-cell gene expression analyses of human cerebrovascular cells can help reveal new drug targets for Huntington’s disease and other neurodegenerative diseases
While neurons and glial cells are by far the most numerous cells in the brain, many other types of cells play important roles. Among those are cerebrovascular cells, which form the blood vessels that deliver oxygen...
Read More »UCLA researcher connecting Statistics and Biology
An interdisciplinary expert in statistics and genomics, Jingyi “Jessica” Li will write the first book to clarify common confusions in genomics data analysis by connecting cutting-edge genomics research...
Read More »Single-cell RNA sequencing reveals mechanism that causes both inflammation and immunosuppression in tumors
If cancerous cells started wreaking havoc in your body, like terrorists in a building, your immune system would act like a SWAT team to combat the enemy. But what if the building entrance were...
Read More »Mount Sinai researchers discover genes that predict good response to blood cancer therapy
Mount Sinai researchers have for the first time identified genes that predict a good response to a vital new therapy for a blood cancer that can...
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