A research team led by Prof. XUE Yuanchao from the Institute of Biophysics of the Chinese Academy of Sciences has developed a new method for global...
Read More »Novel machine-learning algorithm creates atlas of cancer with potential as universal diagnostic platform
In the first broad comparison of pediatric and adult cancer, researchers at The Hospital for Sick Children (SickKids) have analyzed 13,000 individual cancers and built an "atlas" of pediatric cancer using a novel...
Read More »Long noncoding RNA profiling may be effective for stratification in pediatric AML
A single-assay system that incorporates long noncoding RNA expression appears to effectively predict disease prognosis among pediatric patients...
Read More »Single-nucleus transcriptomics reveals new understanding of how androgen therapy affects breast tissue
Insights from the study of transgender men undergoing androgen therapy may help scientists learn how to use the hormone to prevent or fight a type of breast cancer that is fueled by estrogen...
Read More »The power of scRNA-seq in guiding the development of CAR-T cell therapy
Acute myeloid leukemia (AML) is a type of cancer that affects the bone marrow and blood. It is a very aggressive cancer and has a high mortality rate...
Read More »New scientific evidence emerges on how individuals transition from recreational to compulsive use of drugs
Fundamental to the study was RNA sequencing on six regions of the rodent’s brain reward circuitry after cocaine self-administration, withdrawal, and relapse. While substance use disorder (SUD) remains a...
Read More »RNA sequencing technologies provide deeper insights into bacteria
RNA sequencing technologies provide valuable insights into how individual cells work. A research team at the University of Würzburg has now...
Read More »Yale team co-maps proteins and transcriptome in human tissues with spatial CITE-seq
To understand how cells behave, researchers also need to understand the molecules that make them work. “If someone wants to know how the kidney...
Read More »Spatial transcriptomics—the next evolution of cancer drug discovery
Charles Darwin’s theory of evolution was inspired by the diverse species of finches inhabiting the Galápagos Islands. Darwin’s finches evolved from a species that arrived on the islands millions of years...
Read More »Improving diagnosis of genetic diseases with RNA sequencing
The use of next-generation sequencing (NGS) has simplified the diagnosis of human genetic disorders. Since the mapping of the human genome, scientists have been able to detect diseases even at a “single gene” level. While DNA-sequencing provides information about the ...
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