Most models of how tumors evolve have assumed that the process is based predominately on cancer cells’ genetics, and many cancer treatments are...
Read More »Single-cell transcriptomics identifies a gene as a potential target in treatment-resistant brain cancer
Research led by doctors and scientists at UCLA Jonsson Comprehensive Cancer Center and the UCLA Jane & Terry Semel Institute for Neuroscience & Human Behavior have identified a gene that may provide...
Read More »AMP offers recommendations for in silico approaches for validating NGS analysis pipelines
As more laboratories around the country use in silico data to simulate variants to help validate the performance of clinical NGS data analysis pipelines...
Read More »Mathematical model could bring us closer to effective stem cell therapies
The model could allow scientists to finally figure out the order of genetic operations inside developing cells. Stem cells are the very definition of potential...
Read More »Researchers build understanding of the virus universe using metatranscriptome mining
A team of researchers from the National Library of Medicine (NLM) and collaborating academic research institutions have discovered new RNA bacteriophages, viruses that attack bacteria, advancing understanding of virus evolution. Findings were published in the journal Cell. Viruses are considered the most ...
Read More »Genetic sequencing could contain future COVID-19 variants
Standard methods that first assess a new variant’s severity are too slow to stop its spread. Next-generation genetic sequencing, however, offers a feasible alternative to spot new variants...
Read More »Light-Seq – turning the spotlight on cells in tissues so RNA can tell their story
Full-transcriptome sequencing of hard-to-access cells in intact tissues facilitates deeper understanding of disease and biology Under the microscope, researchers often observe different cell types organizing themselves in peculiar patterns within tissues, or sometimes a rare cell type that stands out ...
Read More »New programmable RNA-based tool can monitor and manipulate cells
Duke University researchers have developed an RNA-based editing tool that targets individual cells, rather than genes. It is capable of precisely targeting any...
Read More »RNA sequencing identifies flu-fighting pathways and genes essential for influenza A immune defense
Researchers have identified the gene TDRD7 as a key regulator against influenza A virus (IAV), which causes respiratory tract infections in 5 to 20 percent of the human population. These findings...
Read More »New type of RNA discovered
Novel immunostimulatory dsRNAs activate antiviral responses against multiple pandemic viruses in mouse and human organ chip models. RNA is often described as the single-stranded cousin of DNA, the double-stranded molecule that makes up the genomes of all living organisms. Many ...
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