Commentary

from GenomeWeb by Monica Heger NEW YORK (GenomeWeb) – Researchers from Massachusetts General Hospital have described a method behind two clinical cancer assays — a targeted RNA-seq fusion assay and a hotspot mutation assay — each of which the team ...

from The Scientist by Kate Yandell Researchers create a phylogenetic tree of insects by comparing the sequences of 1,478 protein-coding genes among species. The study authors, who are part of an international consortium working on the 1K Insect Transcriptome Evolution ...

from UT San Diego By Bradley J. Fikes A super-fast genome processor called the Dragen Bio-IT Processor is now on sale by San Diego’s Edico Genome. The processor, which is sold on a standard PCIe computer board, is meant to ...

from Genetic Engineering News by Jonas Korlach Long-Read Sequencing Can Offer the Most Comprehensive View Yet of Gene Activity Not too long ago, the life sciences community was still debating whether sequencers would ever overtake microarrays as the preferred means ...

Guidelines for determining sequencing depth facilitate transcriptome profiling of single cells in heterogeneous populations. In recent years, single-cell RNA-seq has emerged as a powerful, new approach for characterizing the cell types present in a mixed population. These studies usually involve ...

from Oncology Nurse Advisor by Kathy Boltz, PhD Analysis of circulating tumor cells (CTCs) in a mouse model of pancreatic cancer identified distinct patterns of gene expression in several groups of CTCs, including significant differences from the primary tumor that ...

from Nature Methods The past decade has seen a transformation, fueled by the availability of NGS platforms, in applications based on generating DNA and RNA sequence. There are more than 50 multiletter-acronym or ‘MLA-seq’ applications for interrogating a wide variety ...

from the Harvard Gazette by Peter Reuell, Harvard Staff Writer Two groups of Harvard scientists will be among the first researchers nationwide to receive grant funding through the BRAIN (Brain Research through Advancing Innovative Neurotechnologies) Initiative launched last year by ...

Israeli-led research finds circular RNA puts brakes on gene expression, could cause degenerative disease from Times of Israeli by Andrew Tobin An Israeli-led research team has discovered how a mysterious circular type of genetic molecule is produced, and that might ...

from Genetic Engineering News RNA sequencing (RNA-seq), a means of depicting the transcriptome, is being used with increasing frequency to characterize a growing array of conditions—everything from prenatal birth defects to disorders of the elderly. Yet the technique, which is ...