Commentary

Single-cell RNA sequencing reveals 40 different cell types in Stylophora pistillata, a reef-building stony coral native to the Indo-Pacific oceans. The calcium carbonate skeleton of stony coral colonies are the...

Nanopore technology shows promise for making it possible to develop small, portable, inexpensive devices that can sequence DNA in real time. One...

Age may adversely affect women’s fertility by impairing levels of RNA molecules which in turn alter the function of genes involved in key biological...

Neurons result from a highly complex and unique series of cell divisions. For example, in fruit flies, the process starts with stem cells that divide into mother cells (progenitor cells), that then divide into precursor cells that eventually become neurons. ...

Researchers examined 14,000 genetic differences between modern humans and our most recent ancestors at a new level of detail. They found that differences in gene activation – not just genetic code – could underlie evolution of the brain and vocal ...

Single cell sequencing and multiplex single‐molecule RNA FISH analyses on SARS‐CoV‐2 infected human intestinal organoids characterize the tropism of SARS‐CoV‐2 and identify strategies developed by the virus to interfere with the host intrinsic innate...

In a new paper published in Nature Communications, Mayo Clinic researchers and collaborators report the protein-coding gene SERPINA5 may worsen tau protein tangles, which are characteristic of Alzheimer’s disease, and...

Using next-generation RNA sequencing, the UPSeq test assesses 15 biomarkers to find aggressive prostate cancer that can be missed by biopsies or...

Disseminated tumors in metastatic prostate cancer (mPC) share a common monoclonal origin. However, the selective pressure exerted by therapies promotes diversity as resistance mechanisms emerge. This heterogeneity adds to the already diverse spectrum of...

Kidney tissue is very heterogenous with >30 different distinct cell types. This has made it difficult to define molecular fingerprints of individual renal...