Commentary

A clinical research team leads the discovery of applying amniotic fluid cells obtained during 16-24 weeks of pregnancy as a novel sample type for RNA-sequencing in prenatal diagnosis to help more families with tailored clinical management. It is the first...

tRNA-MaP can rapidly analyze the specificity of tRNA m1A22 methyltransferase (TrmK) for substrate tRNAs Genetic information encoded in genomic...

Imagine a virtual human body, rich in complexity and detail, that enables scientists to simulate experiments that can’t be conducted in vivo or...

Researchers from Children’s Hospital of Philadelphia (CHOP) and New Jersey Institute of Technology (NJIT) developed new software that integrates a variety of information from a single cell, allowing...

UCSF researchers identify the cellular source of recurrent glioma. they found that phenotype switching, as opposed to genetic evolution, may be the escape mechanism that explains the failure of...

Single-cell RNA sequencing is becoming a workhorse of transcriptomics, giving researchers details on transcription in individual cells and a sense of both tissue-level heterogeneity and how many cell types...

The application of single-cell RNA sequencing in COVID-19 research has greatly improved our understanding of COVID-19 pathogenesis and immunological characteristics. In this commentary, researchers from the University of Texas Health Science Center at Houston discuss the current challenges, limitations, and ...

Treatments targeting the androgen receptor have extended the lives of people with advanced prostate cancer. At first, prostate cancers need androgens...

Scientists investigate how genes in some insects can influence one another to change their expression depending on environmental conditions...

Late prenatal development of the human neocortex encompasses a critical period of cortical expansion and glial development (cells that are essential to the central nervous system), which is poorly understood...