Commentary

In the fast-paced field of single-cell biology, studies that compare methods can help scientists to pick the right technique for their research. Single-cell biology has exploded over the past decade. Between 2015 and 2021, studies in the PubMed database of ...

Single-cell atlases promise to provide a ‘missing link’ between genes, diseases and therapies. By identifying the specific cell types, states, programs and contexts where disease-implicated genes act...

Although COVID-19 is primarily a respiratory disease, neurological symptoms have been described in many COVID-19 patients, including in recovered...

Periprosthetic joint infection (PJI) is a devastating complication of knee and hip replacement surgery that can, in some cases, be difficult to distinguish...

UCSC scientists point to introners as the source of the vast majority of introns, a source of molecular complexity unique to eukaryotes One of the most long-standing, fundamental mysteries of biology surrounds the poorly understood origins of introns. Introns are ...

For his work in developing Record-seq, a breakthrough technology that records the activities of microbiota in the gut noninvasively and furthers the understanding of gastrointestinal health, Florian Schmidt is the grand prize winner of the 2022...

With development of many effective approaches to fighting cancer, the focus becomes less about finding new ways to treat patients and more about identifying which already available treatments a patient will respond best to. Immune checkpoint inhibitors have...

Why do men have worse outcomes than women from COVID-19? A new study suggests it’s not something wrong with males, it’s something right with females. Specifically, females’ innate immune...

A new statistical method provides a more efficient way to uncover biologically meaningful changes in genomic data that span multiple conditions — such as cell types or tissues. Whole genome studies...

New study uses postmortem brain tissues to understand genomic differences in individuals with attention deficit hyperactivity disorder. Researchers at the National Institutes of Health have...