Researchers at the Icahn School of Medicine at Mount Sinai in New York have identified 35 genes that are particularly highly expressed in people with long-term Lyme disease. These genes could...
Read More »New methods maps how breast cancer spreads
New technology can trace which populations of breast cancer cells are responsible for the spread of the disease, and for the first time highlights how the location of cancer cells could be as important as...
Read More »Covid virus alters RNA in infected cells
For the first time, scientists at the Federal University of São Paulo (UNIFESP) in Brazil have shown that infection by SARS-CoV-2, the virus that causes COVID-19, changes the functioning of host cell RNA. They arrived at this conclusion by analyzing ...
Read More »The untapped potential of RNA structures
The human genome has just over 20,000 genes coding for proteins. Yet, it produces at least ten times that many different non-coding RNA molecules, which can often take on more than one shape. At least some of this RNA structurome ...
Read More »Second-generation single-cell sequencing resolves plant specific cell type subpopulations
While recent advances in plant single-cell RNA sequencing (scRNA-seq) have made numerous strides in identifying novel regulatory events...
Read More »Spatial total RNA-sequencing shows role of elusive RNA in muscle regeneration
In recent years, scientists who study gene expression in cells have used a method that essentially pins a tail on RNA and tracks their...
Read More »Researchers have created a catalog of RNA editing sites in the brain
Mount Sinai researchers have catalogued thousands of sites in the brain where RNA is modified throughout the human lifespan in a process known...
Read More »RNA-sensing system measures and controls protein expression in cells
A new technology called RADARS allows scientists to detect and target specific cell types, opening up potential applications in diagnostics and therapeutics. Researchers at the Broad Institute of...
Read More »Single-cell RNA-sequencing reveals pathways for aggressive prostate cancer subtype
Cribriform prostate cancer is an aggressive subtype of the disease characterized by its histology, but little is known about its molecular pathways. Research...
Read More »A comparison of whole genome and whole transcriptome sequencing reveals phenotypic variation in cancer cells often not due to mutations
Most models of how tumors evolve have assumed that the process is based predominately on cancer cells’ genetics, and many cancer treatments are...
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